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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Cruzado, J. M. Fernandez, L. Riera, L. Bestard, O. Carrera, M. Torras, J. Gil Vernet, S. Melilli, E. Ngango, L. Grinyó, J. M. |
| Spatial Coverage | Spain |
| Description | Country affiliation: Spain Author Affiliation: Cruzado JM ( Department of Nephrology, Hospital Universitari de Bellvitge, IDIBELL, Universitat de Barcelona, Barcelona, Spain. jmcruzado@bellvitgehospital.cat) |
| Abstract | Double kidney transplantation is an accepted strategy to increase the donor pool. Regarding older donor kidneys, protocols for deciding to perform a dual or a single transplantation are mainly based on preimplantation biopsies. The aim of our study was to evaluate the long-term graft and patient survivals of our 'Dual Kidney Transplant program.' Patients who lost one of their grafts peritransplantation were used as controls. A total of 203 patients underwent kidney transplantation from December 1996 to January 2008 in our 'old for old' renal transplantation program. We excluded 21 patients because of a nonfunctioning kidney, hyperacute rejection, or patient death with a functioning graft within the first month. Seventy-nine among 182 kidney transplantation the 'old for old' program were dual kidney transplantation (DKT). Fifteen of 79 patients lost one of their kidney grafts (the uninephrectomized (UNX) UNX group). At 1 year, renal function was lower and proteinuria greater among the UNX than the DKT group. Patient survival was similar in both groups. However, death-censored graft survival was lower in UNX than DKT patients. The 5-year graft survival rate was 70% in UNX versus 93% in DKT cohorts (P = .04). In conclusion, taking into account the kidney shortage, our results may question whether the excellent transplant outcomes with DKT counter balance the reduced donor pool obviating acceptable transplant outcomes for more patients with single kidney transplantation. |
| File Format | HTM / HTML |
| ISSN | 00411345 |
| Issue Number | 6 |
| Volume Number | 43 |
| e-ISSN | 18732623 |
| Journal | Transplantation Proceedings |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-07-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Transplantation__semicolon__medicine Graft Survival Kidney Transplantation Tissue Donors Supply & Distribution Aged Analysis Of Variance Chi-square Distribution Female Humans Kaplan-meier Estimate Adverse Effects Mortality Male Middle Aged Proteinuria Etiology Risk Assessment Risk Factors Spain Survival Rate Time Factors Treatment Outcome Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Transplantation Surgery |
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