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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Pefura-Yone, Eric Walter Kengne, André Pascal Balkissou, Adamou Dodo Magne-Fotso, Christiane Gaelle Ngo-Yonga, Martine Boulleys-Nana, Julie Raïcha Efe-de-Melingui, Nelly Rachel Ndjeutcheu-Moualeu, Patricia Ingrid Mbele-Onana, Charles Lebon Kenmegne-Noumsi, Elvira Christelle Kolontchang-Yomi, Barbara Linda Theubo-Kamgang, Boris Judicaël Ebouki, Emilienne Régine Djuikam-Kamga, Chrystelle Karen Amougou, Francine Mboumtou, Liliane Petchou-Talla, Elsie Linda Kuaban, Christopher |
| Abstract | Background Obstructive lung disease (OLD), a major global public health problem, has been less investigated in African countries. We assessed the prevalence and determinants of OLD in Yaounde (the capital city of Cameroon), using internationally agreed definitions. Methods Participants were adults (age >19 years) screened during a community-based survey between December 2013 and April 2014. Air flow limitation (AFL) was based on a pre-bronchodilator forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) below the lower limit of normal (LLN, AFL–LLN). Chronic obstructive pulmonary disease (COPD) was based on post-bronchodilator FEV1/FVC ratio < LLN (COPD–LLN). Results Of the 1287 subjects included, 51.9 % were female, 9.3 % were current smokers and their mean age was 34.4 ± 12.8 years. Forty-nine (3.8 %, 95 % CI 2.8–4.9 %) participants had AFL–LLN. Thirty-one subjects had COPD–LLN; giving a prevalence of COPD–LLN of (2.4 %, 95 % CI 1.6–3.3 %). In multivariable analysis, male gender (AOR 2.42; 95 % CI 1.12–5.20) and lifetime wheezing (AOR 2.88; 95 % CI 1.06–7.81) were the determinants of COPD-LLN. Otherwise, male sex (AOR 1.93, 95 % CI 1.00–3.73), age 40–59 years (AOR 1.99, 95 % CI 1.04–3.81) and lifetime wheezing (AOR 2.65, 95 % CI 1.13–6.20) remained as independent determinants of AFL–LLN. Conclusions Obstructive lung disease based on more accurate definitions was relatively infrequent in this population. It is important to sensitize the medical staff and the general public about this condition which should be actively investigated in individuals aged 40 years and above. |
| Related Links | https://bmcresnotes.biomedcentral.com/counter/pdf/10.1186/s13104-015-1731-6.pdf |
| Ending Page | 10 |
| Page Count | 10 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 17560500 |
| DOI | 10.1186/s13104-015-1731-6 |
| Journal | BMC Research Notes |
| Issue Number | 1 |
| Volume Number | 9 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2016-02-25 |
| Access Restriction | Open |
| Subject Keyword | Biomedicine Medicine Public Health Life Sciences COPD Air flow limitation Associated factors Africa Medicine/Public Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry, Genetics and Molecular Biology Medicine |
| Journal Impact Factor | 1.6/2023 |
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