NDLI: Ultrasound image-based paravertebral nerve block combined with general anesthesia in laparoscopic radical resection of esophageal cancer

Content Provider	Springer Nature : BioMed Central
Author	Yang, Tingting He, Yuan
Abstract	Background Thoracic epidural analgesia (TEA) is the gold standard for analgesia after thoracotomy, but it has limitations. There are few studies on the analgesic effect of ultrasound-guided paravertebral nerve block (PVB) combined with general anesthesia in esophageal cancer surgery. Methods 52 TLE patients from November 2020 - November 2021 were randomly divided into Group G (general anesthesia, n = 26) and Group G + P (ultrasound - guided PVB + general anesthesia, n = 26). General data, intraoperative/postoperative indicators, VAS scores, HR, MAP, NTI, and patient satisfaction were recorded. Results There were no significant differences in general data such as age, gender, BMI, and ASA grade between the two groups (P > 0.05). The intraoperative dosages of propofol, remifentanil, and sufentanil in Group G + P were significantly lower than those in Group G, while the dosage of phenylephrine was higher. The extubation time, PACU stay time, and postoperative hospital stay in Group G + P were shorter, the dosage of sufentanil in PACU was less, and the incidence of agitation was lower. The VAS scores of Group G + P in the resting and coughing states at multiple time points such as waking up, leaving the PACU, and after surgery were significantly lower than those of Group G. There was no significant difference in HR between the two groups at most time points during the operation. The MAP of Group G was higher than that of Group G + P at time points t8 and t9, and there were significant differences in NTI between the two groups from t2 to t7. The satisfaction rate of patients in Group G + P (96.14%) was significantly higher than that in Group G (80.76%). Conclusion Ultrasound - guided PVB combined with general anesthesia reduces opioid use, eases pain, lowers agitation, shortens hospital stay, and boosts satisfaction in esophageal cancer surgery patients.
Related Links	https://wjso.biomedcentral.com/counter/pdf/10.1186/s12957-025-03772-8.pdf
Ending Page	12
Page Count	12
Starting Page	1
File Format	HTM / HTML
ISSN	14777819
DOI	10.1186/s12957-025-03772-8
Journal	World Journal of Surgical Oncology
Issue Number	1
Volume Number	23
Language	English
Publisher	BioMed Central
Publisher Date	2025-04-10
Access Restriction	Open
Subject Keyword	Surgical Oncology Ultrasound Paravertebral nerve block General anesthesia Postoperative pain Anesthetic effect
Content Type	Text
Resource Type	Article
Subject	Oncology Surgery
Journal Impact Factor	2.5/2023
5-Year Journal Impact Factor	2.8/2023

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