NDLI: An unusual case of post-menopausal bleeding

Content Provider	Springer Nature : BioMed Central
Author	Purwar, Roli Kanugonda, Jyothi Shukla, Mridula Pandey, Manoj
Abstract	Background Metastasis from Renal cell carcinoma at presentation is seen in nearly one fifth of the patients and commonly occur to lung, bone and liver. Synchronous vaginal and cervical metastasis is extremely rare. Several pathways have been proposed of which blood reflux from left renal vein to ovarian vein is most plausible. The prognosis is usually very poor as they are often associated with disseminated metastasis. Case presentation A 55-year-old women presented with post-menopausal vaginal bleeding, on examination a smooth mass occupying the vagina and obscuring the view of cervix with normal mucosa was found. Biopsy and Immunohistochemistry showed it to be renal cell carcinoma. Further investigations lead to identification of left renal mass with pulmonary, vaginal and cervical metastasis. Patient was started on Pazopanib 800 mg PO per day, and was lost to follow-up. Conclusion Vaginal metastasis presenting as post-menopausal bleeding is one of the rarest presentation of renal cell carcinoma with only 3 cases reported in literature before this. Metastatic tumors to the vagina are more common than primary tumors and are mostly from cervix, endometrium and ovary. A high index of suspicion and through examination and investigation is the key to correct diagnosis and management.
Related Links	https://wjso.biomedcentral.com/counter/pdf/10.1186/s12957-025-03684-7.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
ISSN	14777819
DOI	10.1186/s12957-025-03684-7
Journal	World Journal of Surgical Oncology
Issue Number	1
Volume Number	23
Language	English
Publisher	BioMed Central
Publisher Date	2025-02-04
Access Restriction	Open
Subject Keyword	Surgical Oncology Renal cell carcinoma Vaginal metastasis Venous reflux Cervix Kidney Pazopanib
Content Type	Text
Resource Type	Case study
Subject	Oncology Surgery
Journal Impact Factor	2.5/2023
5-Year Journal Impact Factor	2.8/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Renal metastasis after esophagectomy of esophageal squamous cell carcinoma: a case report and literature review

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

Interventional embolization for the treatment of uncontrollable bleeding caused by vaginal metastasis from renal cell carcinoma: A rare case report

Two cases of gallbladder metastasis from renal cell carcinoma and review of literature

Vaginal implantation metastasis of endometrial carcinoma: A case report.

Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy

Renal cell carcinoma: an unusual case of sclerotic metastasis.

Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report

Metastatic squamous cell carcinoma from hand skin causing small bowel obstruction: an unusual case presentation

An unusual case of post-menopausal bleeding

Similar Documents

Renal metastasis after esophagectomy of esophageal squamous cell carcinoma: a case report and literature review

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

Interventional embolization for the treatment of uncontrollable bleeding caused by vaginal metastasis from renal cell carcinoma: A rare case report

Two cases of gallbladder metastasis from renal cell carcinoma and review of literature

Vaginal implantation metastasis of endometrial carcinoma: A case report.

Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy

Renal cell carcinoma: an unusual case of sclerotic metastasis.

Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report

Metastatic squamous cell carcinoma from hand skin causing small bowel obstruction: an unusual case presentation

An unusual case of post-menopausal bleeding