NDLI: The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?

Content Provider	Springer Nature : BioMed Central
Author	Diamandis, Eleftherios P
Abstract	The Hundred Person Wellness Project is an ambitious pilot undertaking, which aims to intensely monitor 100 individuals over 10 months. Patients with abnormal findings will be treated, in hopes that this early intervention will avoid, or delay, symptomatic disease. Google’s “Baseline Study” is of similar scope and will enroll 10,000 people over 2 to 3 years. I here speculate that these approaches will likely not be effective in preventing disease, but instead, lead to unnecessary and potentially harmful interventions. Examples from the cancer screening experience over the last 30 years are provided, which show that intensive testing may uncover indolent disease or incidental findings which, when treated, may cause more harm than good. Additional examples show that aggressive treatments for cancer and other diseases do not always lead to better patient outcomes. I conclude that the recent advances in omics provide us with unprecedented opportunities for high content clinical testing, but such testing should be used with caution to avoid the harmful consequences of over-diagnosis and over-treatment. Despite the detailed rebuttals by Hood and colleagues in another commentary in BMC Medicine, time will show the actual benefits and harms of these ambitious initiatives.Please see related commentary: http://dx.doi.org/10.1186/s12916-014-0238-7
Related Links	https://bmcmedicine.biomedcentral.com/counter/pdf/10.1186/s12916-014-0239-6.pdf
Ending Page	5
Page Count	5
Starting Page	1
File Format	HTM / HTML
ISSN	17417015
DOI	10.1186/s12916-014-0239-6
Journal	BMC Medicine
Issue Number	1
Volume Number	13
Language	English
Publisher	BioMed Central
Publisher Date	2015-01-09
Access Restriction	Open
Subject Keyword	Medicine Public Health Biomedicine Cancer screening Incidental findings Indolent disease Over-diagnosis Over-treatment Population screening Medicine/Public Health
Content Type	Text
Subject	Medicine
Journal Impact Factor	7.1/2023
5-Year Journal Impact Factor	8.8/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?

In with acute bronchitis; out with duodenal perforation: the potentially harmful cascade of over-testing. A case report

Incidental findings, genetic screening and the challenge of personalisation

Commercial ties may be fueling unnecessary and potentially harmful osteoporosis treatment

From screening to treatment: the new landscape of diabetic kidney disease

Evaluation of surgical treatment for incidental gallbladder carcinoma diagnosed during or after laparoscopic cholecystectomy: single center results

HPV testing in Polish population-based cervical cancer screening programme (HIPPO project)—study protocol of a randomised healthcare policy trial

Congenital heart disease: screening, diagnosis, treatment

Congenital heart disease: information for health professionals

The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?

Similar Documents

The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?

In with acute bronchitis; out with duodenal perforation: the potentially harmful cascade of over-testing. A case report

Incidental findings, genetic screening and the challenge of personalisation

Commercial ties may be fueling unnecessary and potentially harmful osteoporosis treatment

From screening to treatment: the new landscape of diabetic kidney disease

Evaluation of surgical treatment for incidental gallbladder carcinoma diagnosed during or after laparoscopic cholecystectomy: single center results

HPV testing in Polish population-based cervical cancer screening programme (HIPPO project)—study protocol of a randomised healthcare policy trial

Congenital heart disease: screening, diagnosis, treatment

Congenital heart disease: information for health professionals

The hundred person wellness project and Google’s baseline study: medical revolution or unnecessary and potentially harmful over-testing?