NDLI: Unveiling China’s heart disease challenges: a comprehensive retrospective study on national mortality burden

Content Provider	Springer Nature : BioMed Central
Author	Yang, Yunjuan Min, Jieqing Zha, Yuanyi
Abstract	Background Heart disease has been the leading cause of death in China since 2020. With the development of the aging population, dietary habits changes, and extreme climate conditions, this study aimed to evaluate national and sub-national changes in the heart disease burden from 2013 to 2021 in china, using data from the National Mortality Surveillance System. Methods This study was mainly using the National Mortality Surveillance System, which covered 300 million, accounted for 24% of China’s population, with national and provincial representativeness from 2013 to 2021. The data categories were modified in 2013 to contain individual classes for heart disease, and the classifications remained consist until 2021. Permutation test were used to identify the Joinpoints in the data. Trends for the study period were evaluated using the average annual percent change (AAPC) in mortality rates with 95% Confidence interval (CI). A decomposition analysis was used to analyse the drivers of mortality change due to heart disease. Results The total number of heart disease related deaths increased from 277,312(2013) to 463,314(2021). The proportion of deaths due to heart disease increased from 21.81% to 25.45%. And the gender-standardized mortality of heart disease increased from 140.11/100,000 to 180.67/100,000 from 2013 to 2021. The average annual increase (AAI) was 4.46%. since 2020, the heart disease has become the leading cause of death, rising from the third place. Epidemic characteristics were as follows: First, the heart disease-related mortality was higher in males than in females. And the AAPC for males was 3.74% from 2013 to 2021 (AAPC = 3.744, 95% CI: 3.048 ~ 4.528, P < 0.01). The AAPC for females was 4.09% (AAPC = 4.088, 95% CI: 2.962 ~ 5.313, P < 0.01). Second, a rapid increase in heart disease related mortality has been observed among 15–44 years population in recent years. Third, the mortality of rural residents in the past 6 years has increased fast (from 151.19/100,000 to 188.58/100,000). The average annual increase in rural heart disease mortality was 3.49%. Fourth, heart disease mortality in Central China increased fast and reached the highest rate in China. Additionally, ischemic heart disease mortality showed the highest, with a rapidly increasing trend. Finally, most heart disease related deaths occurred from October of the first year to March of the following year, with peaks in January and February. And over 70% of these deaths occured at home or in hospital,. Conclusions The deaths due to heart disease indicated a remarkable continues increase in the burden of heart disease. This study results imply escalating healthcare expenses, with projections indicating even greater future challenges. These findings will also help identify gaps in heart disease healthcare and guide the prioritization of health programs dirven by the needs of China.
Related Links	https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-025-21710-x.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	14712458
DOI	10.1186/s12889-025-21710-x
Journal	BMC Public Health
Issue Number	1
Volume Number	25
Language	English
Publisher	BioMed Central
Publisher Date	2025-03-04
Access Restriction	Open
Subject Keyword	Public Health Medicine Epidemiology Biostatistics Vaccine Environmental Health Heart disease Mortality Epidemic trends A comprehensive retrospective study Disease burden Medicine/Public Health
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health
Journal Impact Factor	3.5/2023
5-Year Journal Impact Factor	3.9/2023

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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