NDLI: GeneONE Portal Framework for integrating Genome Databases, tools, techniques and methods

Content Provider	IEEE Xplore Digital Library
Author	Hanifa, G.M. Lee Sai Peck
Copyright Year	2006
Description	Author affiliation: Univ. of Malaya, Kuala Lumpur (Hanifa, G.M.; Lee Sai Peck)
Abstract	The integration of genome databases is as one of the complex and challenges to bioinformatics. It is very important to study the complexity of the nature of the data first in the development of any applications. There are several hundred biological databases, analysis tools are available in the online and are freely accessible for the researcher. However, data integration is a difficult task due to the heterogeneity of the resources. Data in biological databases describes many different "things": DNA sequences, protein structures, biological pathways, protein interactions, gene expression arrays, references to literature, genomic maps, taxonomies and ontologies, etc.The goal of this research work is to combining these different things and the tools under one portal is the driving force behind data integration, but the existing heterogeneity is also a huge handicap due to the many syntactic, structural, and semantic differences. This research work mainly focused to design an integrated framework on genome databases, on several aspects of data integration, gene onthology, identifying an appropriate tool to annotate , analysis gene expression and micro array data.
Starting Page	481
Ending Page	484
File Size	71182
Page Count	4
File Format	PDF
ISBN	9789810579
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-12-11
Publisher Place	Singapore
Access Restriction	Subscribed
Rights Holder	NTU
Subject Keyword	Proteins Data analysis Sequences Databases Taxonomy Genomics DNA Gene expression Bioinformatics Portals
Content Type	Text
Resource Type	Article

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