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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Lee, Y. Famouri, P. |
| Copyright Year | 2011 |
| Description | Author affiliation: Lane Department of Computer Science & Electrical Engineering, West Virginia University, Morgantown, 26506-6109, USA (Lee, Y.; Famouri, P.) |
| Abstract | To demonstrate unidirectional transport using actomyosin system in vitro, polarized F-actin pathway is essential. Polarized F-actin pathway whose ends are immobilized using biotinylated actin-capping proteins on a surface can provide directional movement of myosin coated microbeads. Creating polarized F-actin pathway requires the generation of proper flows in which flow speed and direction in high ionic solution is critical. In the present work, various AC electrokinetic pump designs are investigated to create a flow field in a microchannel. Moreover, the polarity of F-actin is determined using SEM. Once these two techniques are established, it will help the development of a device utilizing actomyosin system. This investigation will lay foundation for the future applications of autonomous transport and actuation systems, whether biological or synthetic in nature at nanoscale. |
| Starting Page | 30 |
| Ending Page | 33 |
| File Size | 830025 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781457715143 |
| ISSN | 19449399 |
| e-ISBN | 9781457715167 |
| e-ISBN | 9781457715150 |
| DOI | 10.1109/NANO.2011.6144431 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-08-15 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Electrokinetics Electrodes Microfluidics Surface treatment Arrays Scanning electron microscopy Pumps SEM myosin actin array AC electrokinetic pump transport structural polarity |
| Content Type | Text |
| Resource Type | Article |
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