NDLI: Event-by-event motion compensation for small animal PET

Content Provider	IEEE Xplore Digital Library
Author	Zhou, V.W. Kyme, A.Z. Meikle, S.R. Fulton, R.R.
Copyright Year	2007
Description	Author affiliation: Univ. of Sydney, Sydney (Zhou, V.W.; Kyme, A.Z.)
Abstract	In small animal PET imaging anaesthesia is usually required to eliminate motion. However, both anaesthesia and the alternative of forcibly restraining the animal, can disturb the very biochemical pathways that are of most interest in the brain. The ability to image the awake animal would represent a major advance. To this end we have investigated a motion correction technique suitable for small animal imaging on the microPET scanner, based on previous successful work in human brain PET. The efficacy of our technique was assessed on the microPET system by applying movements to a micro hot rod phantom during list mode acquisition. Movements of the phantom in scanner coordinates were obtained using a commercially available optical motion tracking system operating in the visible spectrum. Motion correction, applied as corrective spatial transformations to individual lines of response, significantly reduced motion distortion. Our immediate goal is to perfect practical methods for marker attachment and motion tracking of small animals during microPET scans.
Starting Page	3109
Ending Page	3114
File Size	565733
Page Count	6
File Format	PDF
ISBN	9781424409228
ISSN	10957863
DOI	10.1109/NSSMIC.2007.4436788
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-10-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Motion compensation Animals Positron emission tomography Optical imaging Tracking Head Humans Physics Australia Telephony
Content Type	Text
Resource Type	Article

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