NDLI: Modeling respiratory motion variations in the 4D NCAT phantom

Content Provider	IEEE Xplore Digital Library
Author	Segars, W.P. Mori, S. Chen, G.T.Y. Tsui, B.M.W.
Copyright Year	2007
Description	Author affiliation: Duke Univ., Durham (Segars, W.P.)
Abstract	The current 4D NCAT phantom includes a flexible, parameterized respiratory model based on respiratory-gated CT data of a normal subject. A limitation of this model is that it is based on only one realization of the normal respiratory motion. The data upon which it was based also had a resolution lower than that offered by more advanced CT scanners and consisted of only four time frames that did not adequately cover normal tidal breathing. We further develop the 4D NCAT to more accurately model normal and abnormal states of respiration. Over two-hundred sets of 4D respiratory gated CT image data from normal and abnormal patients obtained from the Massachusetts General Hospital were used to characterize variations in the respiratory motion. Each dataset contains twenty time frames over the respiratory cycle with the patient breathing normally. With the improved resolution and better coverage of tidal breathing, this data was used to improve the respiratory model of the 4D NCAT phantom. Using automatic and semiautomatic techniques, the different respiratory structures were segmented from each time frame of each CT dataset. The time series of segmented structures were used to characterize the respiratory motion in each case. From an analysis of all normal and abnormal patient datasets, we determined the range of sizes and shapes of the right and left lungs and the range in motion (expansion in the anterior and inferior (diaphragm) directions) in the different lung regions. This analysis was used to further parameterize the general respiratory model of the 4D NCAT to more realistically model normal and abnormal variations in anatomy and in the respiratory motion. With the ability to model variations in the respiratory motion indicative of a patient population, the phantom will be a great resource to investigate the effects of respiratory motion on medical imaging and to develop compensation methods for these effects.
Starting Page	2677
Ending Page	2679
File Size	770854
Page Count	3
File Format	PDF
ISBN	9781424409228
ISSN	10957863
DOI	10.1109/NSSMIC.2007.4436697
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-10-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Imaging phantoms Computed tomography Humans Lungs Motion analysis Anatomy Biomedical imaging Hospitals Spline Image segmentation
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in