NDLI: Diffraction enhanced breast imaging: assessment of realistic system requirements to improve the diagnostic capabilities of mammography

Content Provider	IEEE Xplore Digital Library
Author	Griffiths, J.A. Royle, G.J. Speller, R.D. Horrocks ,. J.A. Olivo, A. Pani, S. Longo, R. Spencer, S.H. Robbins, M.S. Clifford, D.P. Hanby, A.M.
Copyright Year	2004
Description	Author affiliation: Dept. of Med. Phys. & Bioeng., Univ. Coll. London, UK (Griffiths, J.A.; Royle, G.J.; Speller, R.D.)
Abstract	A detectable difference in X-ray diffraction data of healthy and diseased breast tissues has been observed. This information can be used to generate images with a higher contrast than that of conventional transmission mammography. A diffraction enhanced breast imaging (DEBI) system that simultaneously combines transmission and diffraction breast images is currently being developed. This paper presents the imaging system requirements for a clinical DEBI system. The DEBI imaging system employs a phosphor coated L3Vision CCD camera. The DEBI principle has been assessed at the SYRMEP synchrotron beamline (Elettra, Trieste) and with a purpose built mammographic X-ray imaging unit. Diffraction enhanced images have been obtained of realistic breast tissue phantoms, consisting of 4 cm thick slabs of excised breast tissue containing embedded carcinomas. The images were obtained at pre-determined momentum transfer values, allowing some tissue characterization to be achieved during imaging, as well as optimizing image contrast This paper presents the current state of the project. The spatial resolution of the diffraction images have been studied using test phantoms and suggestions are made for the collimation systems necessary for a clinical system. A correction procedure applied to the diffraction images is also presented.
Starting Page	3230
Ending Page	3234
File Size	652548
Page Count	5
File Format	PDF
ISBN	0780382579
ISSN	10823654
DOI	10.1109/NSSMIC.2003.1352586
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-10-19
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Mammography X-ray diffraction Optical imaging Breast tissue X-ray imaging Imaging phantoms X-ray detection X-ray detectors Image generation Phosphors
Content Type	Text
Resource Type	Article

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