NDLI: Evaluating human observer performance for list mode PET using the bootstrap method

Content Provider	IEEE Xplore Digital Library
Author	D'Asseler, Y. Groiselle, C.J. Gifford, H.C. Vandenberghe, S. Van de Walle, R. Lemahieu, I.L. Glick, S.J.
Copyright Year	2004
Description	Author affiliation: The Ghent, Gent, Belgium (D'Asseler, Y.)
Abstract	In an LROC (localization receiver operating characteristic) study, a human observer is presented a number of images, of which some contain a signal within a certain region and some do not contain any signal The observer is asked to give a confidence rating as to the probability of the presence of a signal, and to give the most probable location of the signal. A LROC curve can then be fitted. The area under the LROC gives an indication of the observer performance for the given set of images. A large number of images is needed for a human observer study, e.g. 100 for the study itself and 50 as a training set. The simulation or measurement of all of these images is very time consuming and/or impractical. In a previous paper, we proposed the bootstrap method as a means to create a number of list mode files from one simulation, and showed that these files can be used to evaluate the LROC performance of a CNPW numerical observer. In this paper, we investigate whether the bootstrapped images can be used to evaluate human observer performance. We found that human performance was inferior on bootstrapped images compared to noisy images. However, by substituting for the noisy background with a smoothed version of this background, human observer performance becomes comparable to performance with noisy realizations of the images. We can therefore conclude that bootstrapped images, with a smoothed background, can be used as an alternative for noise realizations for human observer studies.
Starting Page	3070
Ending Page	3073
File Size	319495
Page Count	4
File Format	PDF
ISBN	0780382579
ISSN	10823654
DOI	10.1109/NSSMIC.2003.1352546
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-10-19
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Positron emission tomography Background noise Image quality Biomedical imaging Time measurement Area measurement Cancer Fellows Telephony
Content Type	Text
Resource Type	Article

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