NDLI: RF biosensor based on microwave filter for biological cell characterisation

Content Provider	IEEE Xplore Digital Library
Author	Dalmay, C. Pothier, A. Blondy, P. Cheray, M. Lalloue, F. Jauberteau, M.-O.
Copyright Year	2009
Description	Author affiliation: Homéostasie cellulaire et Pathologies, Université de Limoges 2 rue Doct Marcland, 87000 Limoges, France (Cheray, M.; Lalloue, F.; Jauberteau, M.-O.) \|\| XLIM - UMR 6172 Université de Limoges/CNRS 123 avenue Albert Thomas, 87060 Limoges Cedex, France (Dalmay, C.; Pothier, A.; Blondy, P.)
Abstract	An original new bio-detection method using microwave frequencies has been developed in order to study human cell electrical parameters. The developed biosensor design is based on a two pole microstrip filter architecture using the inter-resonator's planar coupling capacitor as an ultra sensitive biosensing element. In the proposed approach, the bio-detection principle deals with the filter coupling change induced by only few biological cells located on this capacitor. In the present paper, studied cells are grown “on-chip” in the coupling comb capacitor gaps allowing an accurate and sensitive detection at the cell scale. Experimental characterisations results on cancerous glioblatoma human cells are presented showing the biosensor detection capabilities until one single cell detection.
Starting Page	041
Ending Page	044
File Size	790223
Page Count	4
File Format	PDF
ISBN	9781424447480
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-29
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	EUMA
Subject Keyword	Radio frequency Biosensors Microwave filters Biological cells Capacitors Conductivity Cells (biology) Permittivity Band pass filters Resonator filters
Content Type	Text
Resource Type	Article

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