NDLI: Detection and estimation of T wave alternans with matched filter and nonparametric bootstrap test

Content Provider	IEEE Xplore Digital Library
Author	Rojo-Alvarez, J.L. Barquero-Perez, O. Mora-Jimenez, I. Goya-Esteban, R. Gimeno-Blanes, J. Garcia-Alberola, A.
Copyright Year	2008
Description	Author affiliation: Hosp. Univ. Virgen de la Arrixaca, Murcia (Garcia-Alberola, A.) \|\| Univ. Miguel Hernandez, Elche (Gimeno-Blanes, J.) \|\| Univ. Rey Juan Carlos, Madrid (Rojo-Alvarez, J.L.; Barquero-Perez, O.; Mora-Jimenez, I.; Goya-Esteban, R.)
Abstract	Though alternans phenomena in the cardiac repolarization phase has been shown to be related to arrhythmgenesis, a definitive estimation method from the T wave of ECG recordings is not yet available. We propose a statistical signal processing scheme which compares the T-wave morphology of even and odd beats by using a running matched filter, in order to increase the signal to noise ratio of the estimation. Given that previously proposed hypothesis tests for alternans detection rely on the knowledge of noise statistical distribution, we also analyzed the usefulness of a nonparametric bootstrap test. Data set composed of 100 ECG recordings included in the Challenge Database were used. Principal Component Analysis was previously made for multilead recordings. Subsequent preprocessing for each available lead consisted of conventional baseline removing, filtering, R-wave detection, exclusion of too noisy segments, T-wave segmentation, and template generation for even and odd beats. The difference between the template and a given beat was obtained by minimizing the absolute error of their comparison with a windowed circular shift. A paired bootstrap resampling test was made for deciding whether the averaged differences between the template and the T-waves were significant compared to the noise level.
Starting Page	617
Ending Page	620
File Size	1344509
Page Count	4
File Format	PDF
ISBN	9781424437061
ISSN	02766547
DOI	10.1109/CIC.2008.4749117
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-09-14
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Computers in Cardiology(CinC)
Subject Keyword	Matched filters Testing Electrocardiography Phase estimation Signal processing Morphology Signal to noise ratio Statistical distributions Databases Principal component analysis
Content Type	Text
Resource Type	Article

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