NDLI: Non-rigid motion compensation in free-breathing myocardial perfusion magnetic resonance imaging

Content Provider	IEEE Xplore Digital Library
Author	Wollny, G. Ledesma-Carbayo, M.J. Kellman, P. Santos, A.
Copyright Year	2008
Description	Author affiliation: Group of Biomed. Imaging Technol., Univ. Politcnica de Madrid, Madrid (Ledesma-Carbayo, M.J.; Santos, A.) \|\| Lab. of Cardiac Energetics, Lung & Blood Inst., Bethesda, MD (Kellman, P.) \|\| Ciber BNN (Wollny, G.)
Abstract	Breathing movements during the image acquisition of first-pass gadolinium enhanced, magnetic resonance imaging (MRI) hinder a direct automatic analysis of the myocardial perfusion. In addition, a qualitative readout by visual tracking is also more difficult as well. Non-rigid registration can be used to compensate for these movements in the image series. Because of the local contrast and intensity change over time, the registration method needs to be chosen carefully. We propose to make use of the periodicity of the breathing movement when patients are allowed to breath freely during image acquisition. Specifically, we propose to first identify a subset of the images that corresponds to the same phase of the breathing cycle and register these to compensate for the residual differences. By using a combination of normalised gradient fields and the sum of squared differences we circumvent the problems arising from the change of intensity. Then, for each of the remaining images, reference images of a similar intensity distribution are created by a linear combination of images from the align subset. In the last step, registration is achieved by minimising the sum of squared differences. Our first experiments show that this approach is well suited to compensate for the breathing movements.
Starting Page	465
Ending Page	468
File Size	1073685
Page Count	4
File Format	PDF
ISBN	9781424437061
ISSN	02766547
DOI	10.1109/CIC.2008.4749079
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-09-14
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Computers in Cardiology(CinC)
Subject Keyword	Motion compensation Myocardium Magnetic resonance imaging Heart Magnetic analysis Independent component analysis Biomedical imaging Biomedical engineering Laboratories Lungs
Content Type	Text
Resource Type	Article

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