NDLI: Development of a GUI-based platform for analysis of alveolar macrophage cell pH and ion regulation

Content Provider	IEEE Xplore Digital Library
Author	Luo, C. Clark, J.W. Bidani, A.
Copyright Year	2002
Description	Author affiliation: Dept. of Electr. Eng., Rice Univ., Houston, TX, USA (Luo, C.; Clark, J.W.)
Abstract	Mathematical models of complex biological cell systems are an important means to gain insight into the underlying biophysical & biochemical mechanisms that govern cellular homeostasis and regulation. Because of the nonlinear nature of the transport processes, and the multiplicity of mechanisms, these models are often very complex and cumbersome. This often limits their utility in integrated multi-disciplinary studies involving physiologists, engineers and clinicians. In order to allow the broader use of a mathematical model of cell and subcellular pH, ion and volume regulation, we have developed a graphical user interface (GUI), which can serve as a platform for both research and teaching of cell acid-base and ion regulation. Because of the modular nature of the GUI-platform, new complexities (such as calcium regulation) and additional transport mechanisms, including signal transduction pathways, can be easily incorporated.
Starting Page	2678
Ending Page	2679
File Size	173603
Page Count	2
File Format	PDF
ISBN	0780376129
ISSN	1094687X
DOI	10.1109/IEMBS.2002.1053488
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-23
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Graphical user interfaces Mathematical model Extracellular Visualization Java Cells (biology) Biological cells Biological system modeling Education Calcium
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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