NDLI: Bifocal technique for accurate measurement of total attenuation coefficient in scattering media with OCT

Content Provider	IEEE Xplore Digital Library
Author	Kholodnykh, A.I. Petrova, I.Y. Motamedi, M. Esenaliev, R.O.
Copyright Year	2002
Description	Author affiliation: Center for Biomed. Eng., Univ. of Texas Med. Branch, Galveston, TX, USA (Kholodnykh, A.I.; Petrova, I.Y.; Motamedi, M.; Esenaliev, R.O.)
Abstract	Accurate measurements of tissue optical properties are needed for many diagnostic and therapeutic applications of optical techniques. OCT recently proposed for high-resolution imaging in tissue can potentially be applied for accurate and noninvasive measurement of tissue optical properties. We proposed a bifocal technique for accurate measurement of tissue total attenuation coefficient with OCT. This technique utilizes detection of OCT signals from two focal planes within scattering media that allows correction for confocal function. In this paper, we studied the capability of the bifocal technique to measure accurately total attenuation coefficient in scattering media simulating tissue with high and low scattering. The experiments were performed with tissue phantoms: suspension of polystyrene microspheres in water with different total attenuation coefficients. Our studies demonstrated that the bifocal technique substantially improves accuracy of measurement: absolute values of total attenuation coefficient can be measured with 7% accuracy (compared with theoretically calculated values), while the accuracy of relative measurements can be 1.5%. Our results indicate that the bifocal technique is a promising approach to accurate measurement of total attenuation coefficient in tissues.
Starting Page	2251
Ending Page	2252
File Size	228965
Page Count	2
File Format	PDF
ISBN	0780376129
ISSN	1094687X
DOI	10.1109/IEMBS.2002.1053267
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-23
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Attenuation measurement Optical scattering Optical attenuators Biomedical measurements Adaptive optics Biomedical optical imaging Optical interferometry Optical mixing Light scattering Superluminescent diodes
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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