NDLI: Optimization of lithotripter waveform to reduce tissue injury without compromising stone comminution

Content Provider	IEEE Xplore Digital Library
Author	Zhou, Y.F. Zhong, P.
Copyright Year	2002
Description	Author affiliation: Dept. of Mech. Eng. & Mater. Sci., Duke Univ., Durham, NC, USA (Zhou, Y.F.; Zhong, P.)
Abstract	To reduce the potential of vascular injury without compromising stone comminution in shock wave lithotripsy, an in situ pulse superposition technique has been developed to suppress intraluminal bubble expansion by modifying an HM-3 reflector based on theoretical analysis and pressure waveform measurement. Using high-speed imaging, it was found that the large Intraluminal bubble expansion was significantly suppressed using the upgraded reflector. Consequently, no rupture of vessel phantom could be observed near the lithotripter focus even after 200 shocks at 24 kV. In comparison, the vessel phantom could be ruptured within 50 shock using the original HM-3 reflector at 20 kV. At corresponding reflector configurations, stone phantom comminution is comparable up to 2,000 shocks. Furthermore, animal studies have demonstrated a significant reduction in renal injury using the upgraded reflector, which confirms the validity of this approach in vivo.
Starting Page	1795
Ending Page	1796
File Size	282827
Page Count	2
File Format	PDF
ISBN	0780376129
ISSN	1094687X
DOI	10.1109/IEMBS.2002.1053029
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-23
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Lithotripsy Injuries Imaging phantoms Electric shock Pulse measurements Shock waves Pressure measurement Focusing Animals In vivo
Content Type	Text
Resource Type	Article

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