NDLI: A new fully integrated CMOS interface for a dielectrophoretic lab-on-a-chip device

Content Provider	IEEE Xplore Digital Library
Author	Miled, M.A. Sawan, M.
Copyright Year	2011
Description	Author affiliation: Polystim Neurotechnologies Laboratory, Department of Electrical Engineering, École Polytechnique de Montreal, Québec, Canada (Miled, M.A.; Sawan, M.)
Abstract	We present in this paper a new CMOS interface for cell manipulation by dielectrophoresis and capacitive sensing system dedicated for a lab-on-a-chip. It fully integrates a signal generation circuit and a post-processing system to control parameters of each signal such as frequency, phase and amplitude. In addition, a large capacitive and low resistive load driver circuit is designed to deliver a current of 9 mA for each 16 elecrodes as the microfluidic architecture is divided into 4 blocs containing 16 electrodes each one. Thus, the proposed CMOS chip provides 4-channel signals with individually controllable phase and amplitude. In addition, a capacitive sensing system has been integrated into the same chip to detect the capacitive change in the microchannel in the Lab-on-a-chip. The generated signals have a 2.5 peak-to-peak voltage range and 70 kHz frequency range while the detection system has a dynamic range of 1.5 V and a sensitivity of 11.8 ƒF/V.
Starting Page	2349
Ending Page	2352
File Size	1414244
Page Count	4
File Format	PDF
ISBN	9781424494736
ISSN	02714302
e-ISBN	9781424494743
e-ISBN	9781424494729
DOI	10.1109/ISCAS.2011.5938074
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-05-15
Publisher Place	Brazil
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microprocessors CMOS integrated circuits Dielectrophoresis Electrodes Sensors Arrays
Content Type	Text
Resource Type	Article

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