NDLI: Real-Time System for Dosimetry in IORT (Intra Operative Radiation Therapy)

Content Provider	IEEE Xplore Digital Library
Author	Brancaccio, R. Bettuzzi, M. Casali, F. Cornacchia, S. Morigi, M. Pasini, A.
Copyright Year	1963
Abstract	Intra Operative Radiation Therapy (IORT) is a technique based on delivery of a high dose of ionising radiation to the cancer tissue, after tumour ablation, during surgery, while reducing the exposure of normal surrounding tissue. The Novac7 is a new linear accelerator expressly conceived to perform in the operating room. This accelerator supplies electron beams with high dose rate. Because these peculiar characteristics, classical dosimetric techniques are not able to give at once a real-time response and an extensive measure of the absorbed dose. The new system is composed by a grid of scintillating optical fibres coupled with two arrays of photodiodes. The instrument samples the delivered beam at 100 Hz. The dedicated software collects the two projection-signals and reconstructs the bi-dimensional image. Moreover it provides a series of dosimetric parameters. We studied an appropriate reconstruction algorithm searching the best compromise between the computational complexity and an high precision. An accelerator having energies ranging from 3 to 12 MeV has been used for the tests. The system is able to give a real time response (within 30 seconds), the resolution is of 1 millimeter. The response is linear versus dose and the measures are not affected by the high dose rate. The conclusions confirm the capability of the instrument to overcome problems encountered with classic dosimetry, showing that the results obtained strongly encourage the continuation of this research
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	2844
Ending Page	2848
Page Count	5
File Size	1079306
File Format	PDF
ISSN	00189499
Volume Number	53
Issue Number	5
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-10-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Real time systems Dosimetry Biomedical applications of radiation Optical arrays Instruments Ionizing radiation Cancer Tumors Oncological surgery Linear accelerators real-time acquisition Digital system dosimetry electron beam FOS Intra Operative Radiation Therapy (IORT) photodiode array
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

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