NDLI: Folate-modified, indocyanine green-loaded lipid-polymer hybrid nanoparticles for targeted delivery of cisplatin.

Please wait, while we are loading the content...

Scalable preparation of poly(ethylene glycol)-grafted siRNA-loaded lipid nanoparticles using a commercially available fluidic device and tangential flow filtration.

Injectable and biodegradable temperature-responsive mixed polymer systems providing variable gel-forming pH regions.

The unique hydration state of poly(2-methacryloyloxyethyl phosphorylcholine).

Collagen-PVA aligned nanofiber on collagen sponge as bi-layered scaffold for surface cartilage repair.

Preparation of free-standing hybrid colloidal membranes via assembly of liponanocapsules.

The development of polymeric biomaterials inspired by the extracellular matrix.

Biocompatible hyperbranched polyester magnetic nanocarrier for stimuli-responsive drug release.

Folate-modified, indocyanine green-loaded lipid-polymer hybrid nanoparticles for targeted delivery of cisplatin.

On-off affinity binding modulation on thermoresponsive polymer-grafted surfaces for capture and release of proteins and cells.

Fractional laser-assisted percutaneous drug delivery via temperature-responsive liposomes.

Development of a rapid in vitro tissue deadhesion system using the thermoresponsive sol-gel transition of hydroxybutyl chitosan.

Cationic copolymer augments membrane permeabilizing activity of an amphiphilic peptide.

MicroRNA-mediated non-viral direct conversion of embryonic fibroblasts to cardiomyocytes: comparison of commercial and synthetic non-viral vectors.

Heat capacity and nuclear magnetic relaxation times of non-freezing water restrained by polysaccharides, revisited.

Nanofibrous scaffold from electrospinning biodegradable waterborne polyurethane/poly(vinyl alcohol) for tissue engineering application.

In vitro and in vivo evaluation of the chitosan/Tur composite film for wound healing applications.

Improved performance of collagen scaffolds crosslinked by Traut's reagent and Sulfo-SMCC.

An emotional contribution to the Festschrift of the Journal of Biomaterials Science for Teiji Tsuruta.

Cardiovascular Toxicity Assessment of Poly (ethylene imine)- based Cationic Polymers on Zebrafish Model.

Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness.

Fabrication and characterization of chitosan/OGP coated porous poly(Îµ-caprolactone) scaffold for bone tissue engineering.

A cell attracting composite of lumbar fusion cage.

Injectable Conductive Collagen/Alginate/Polypyrrole Hydrogels as a Biocompatible System for Biomedical Applications.

Effect of animal products and extracts on wound healing promotion in topical applications: a review.

Multiboronic acid-conjugated chitosan scaffolds with glucose selectivity to insulin release.

Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery.

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration.

Marine macromolecules cross-linked hydrogel scaffolds as physiochemically and biologically favorable entities for tissue engineering applications.

Oligo(ethylene glycol)-modified ß-cyclodextrin-based polyrotaxanes for simultaneously modulating solubility and cellular internalization efficiency.

Year: 2016 Volume: 27

Year: 2015 Volume: 26

Year: 2014 Volume: 25

Year: 2013 Volume: 24

Year: 2012 Volume: 23

Year: 2011 Volume: 22

Year: 2010 Volume: 21

Year: 2009 Volume: 20

Year: 2008 Volume: 19

Year: 2006 Volume: 17

Year: 2005 Volume: 16

Year: 2001 Volume: 12

Year: 2000 Volume: 11

Folate-modified, indocyanine green-loaded lipid-polymer hybrid nanoparticles for targeted delivery of cisplatin.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Gu, Lianshuai Shi, Tianyi Sun, Yu You, Chaoqun Wang, Senlin Wen, Gaoju Chen, Lan Zhang, Xiangyang Zhu, Jin Sun, Baiwang
Description	Country affiliation: China Author Affiliation: Gu L ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Shi T ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Sun Y ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); You C ( b School of Pharmacy , Wannan Medical College , Wuhu , China.); Wang S ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Wen G ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Chen L ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Zhang X ( a School of Chemistry and Chemical Engineering , Southeast University , Nanjing , China.); Zhu J ( c Laboratory of Organic Chemistry , ETH Zurich , Zurich , Switzerland.); Sun B ( d Huadong Medical Institute of Biotechniques , Nanjing , China.)
Abstract	Cisplatin is a potent antitumor drug, which is widely applied in clinical cancer treatment. However, cisplatin can hardly distinguish between healthy tissue and tumor tissue, resulting in serious toxic side effects. Indocyanine green (ICG) is a FDA-approved near-infrared (NIR) fluorescence dye which has been used in photothermal therapy and optically mediated diagnostic, but the application of ICG is limited by its concentration-dependent aggregation, poor aqueous stability in vitro, lack of target specificity and rapid elimination from the body. Herein, to overcome these limitations of cisplatin and ICG, we fabricated folate-modified, cisplatin, ICG-loaded lipid-polymer hybrid nanoparticles (FCINPs) using a single-step sonication method. The FCINPs exhibited well-defined monodispersity, significant stability and excellent NIR penetration ability. The intracellular uptake experiment showed that the targeting efficacy of the FCINPs was more effective in folate receptors (FRs) over-expressing MCF-7 cells than FRs negative A549 cells. In addition, compared with chemo or photothermal treatment alone, the treatment of FCINPs in combination with 808 nm NIR laser irradiation can significantly induce the apoptosis and necrosis of MCF-7 cells. These findings indicated that the FCINPs would be a promising nanosized drug formulation for tumor-targeted therapy in the future.
File Format	HTM / HTML
ISSN	09205063
Journal	Journal of Biomaterials Science, Polymer Edition
e-ISSN	15685624
Language	English
Publisher	Taylor & Francis
Publisher Date	2017-02-23
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

Folate-conjugated hydrophobicity modified glycol chitosan nanoparticles for targeted delivery of methotrexate in rheumatoid arthritis

Folate-receptor-targeted laser-activable poly(lactide-co-glycolic acid) nanoparticles loaded with paclitaxel/indocyanine green for photoacoustic/ultrasound imaging and chemo/photothermal therapy

Cyclic RGD functionalized PLGA nanoparticles loaded with noncovalent complex of indocyanine green with urokinase for synergistic thrombolysis

Magnetic nanoparticles modified with quaternarized N-halamine based polymer and their antibacterial properties.

iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy.

Evaluation of VCAM-1 Targeted Naringenin/Indocyanine Green-Loaded Lipid Nanoemulsions as Theranostic Nanoplatforms in Inflammation

Scalable preparation of poly(ethylene glycol)-grafted siRNA-loaded lipid nanoparticles using a commercially available fluidic device and tangential flow filtration.

Folate-modified, indocyanine green-loaded lipid-polymer hybrid nanoparticles for targeted delivery of cisplatin.

Similar Documents

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

Folate-conjugated hydrophobicity modified glycol chitosan nanoparticles for targeted delivery of methotrexate in rheumatoid arthritis

Folate-receptor-targeted laser-activable poly(lactide-co-glycolic acid) nanoparticles loaded with paclitaxel/indocyanine green for photoacoustic/ultrasound imaging and chemo/photothermal therapy

Cyclic RGD functionalized PLGA nanoparticles loaded with noncovalent complex of indocyanine green with urokinase for synergistic thrombolysis

Magnetic nanoparticles modified with quaternarized N-halamine based polymer and their antibacterial properties.

iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy.

Evaluation of VCAM-1 Targeted Naringenin/Indocyanine Green-Loaded Lipid Nanoemulsions as Theranostic Nanoplatforms in Inflammation

Scalable preparation of poly(ethylene glycol)-grafted siRNA-loaded lipid nanoparticles using a commercially available fluidic device and tangential flow filtration.

Folate-modified, indocyanine green-loaded lipid-polymer hybrid nanoparticles for targeted delivery of cisplatin.