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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Van Weerd, Jasper Karperien, Marcel Jonkheijm, Pascal |
| Description | Country affiliation: Netherlands Author Affiliation: van Weerd J ( Bioinspired Molecular Engineering, University of Twente, PO Box 217, 7500, AE, Enschede, The Netherlands.); Karperien M ( Dept. of Developmental BioEngineering, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, PO Box 217, 7500, AE, Enschede, The Netherlands.); Jonkheijm P ( Molecular Nanofabrication Group, MESA+, University of Twente, Enschede, 7500, AE, The Netherlands.) |
| Abstract | Supported lipid bilayers (SLB) offer unique possibilities for studying cellular membranes and have been used as a synthetic architecture to interact with cells. Here, the state-of-the-art in SLB-based technology is presented. The fabrication, analysis, characteristics and modification of SLBs are described in great detail. Numerous strategies to form SLBs on different substrates, and the means to patteren them, are described. The use of SLBs as model membranes for the study of membrane organization and membrane processes in vitro is highlighted. In addition, the use of SLBs as a substratum for cell analysis is presented, with discrimination between cell-cell and cell-extracellular matrix (ECM) mimicry. The study is concluded with a discussion of the potential for in vivo applications of SLBs. |
| File Format | HTM / HTML |
| ISSN | 21922640 |
| Issue Number | 18 |
| Volume Number | 4 |
| e-ISSN | 21922659 |
| Journal | Advanced Healthcare Materials |
| Language | English |
| Publisher | Wiley-VCH |
| Publisher Date | 2015-12-30 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biomedical Engineering Biocompatible Materials Pharmacology Cells Metabolism Lipid Bilayers Chemistry Animals Drug Effects Extracellular Matrix Humans Membranes, Artificial Journal Article Research Support, Non-u.s. Gov't Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomaterials Biomedical Engineering Pharmaceutical Science |
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