NDLI: Testing likelihood ratios produced from complex DNA profiles.

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Testing likelihood ratios produced from complex DNA profiles.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Taylor, Duncan Buckleton, John Evett, Ian
Description	Author Affiliation: Taylor D ( Forensic Science South Australia, 21 Divett Place, Adelaide, SA 5000, Australia); Buckleton J ( ESR, Private Bag 92021, Auckland 1142, New Zealand.); Evett I ( Principal Forensic Services Ltd., London, UK.)
Abstract	The performance of any model used to analyse DNA profile evidence should be tested using simulation, large scale validation studies based on ground-truth cases, or alignment with trends predicted by theory. We investigate a number of diagnostics to assess the performance of the model using Hd true tests. Of particular focus in this work is the proportion of comparisons to non-contributors that yield a likelihood ratio (LR) higher than or equal to the likelihood ratio of a known contributor (LRPOI), designated as p, and the average LR for Hd true tests. Theory predicts that p should always be less than or equal to 1/LRPOI and hence the observation of this in any particular case is of limited use. A better diagnostic is the average LR for Hd true which should be near to 1. We test the performance of a continuous interpretation model on nine DNA profiles of varying quality and complexity and verify the theoretical expectations.
File Format	HTM / HTML
ISSN	18724973
Journal	Forensic Science International: Genetics
Volume Number	16
e-ISSN	18780326
Language	English
Publisher	Elsevier
Publisher Date	2015-05-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Forensic Sciences Dna Genetics Likelihood Functions Humans Journal Article Research Support, U.s. Gov't, Non-p.h.s.
Content Type	Text
Resource Type	Article
Subject	Genetics Pathology and Forensic Medicine

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