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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bloom, Michael S. Vom Saal, Frederick S. Kim, Dongsul Taylor, Julia A. Lamb, Julie D. Fujimoto, Victor Y. |
| Description | Country affiliation: United States Author Affiliation: Bloom MS ( Department of Environmental Health Sciences, University at Albany, State University of New York, Rensselaer, NY 12144, USA. mbloom@albany.edu) |
| Abstract | Here we assess bisphenol A (BPA) in couples undergoing in vitro fertilization (IVF) and indicators of embryo quality; embryo cell number (ECN) and embryo fragmentation score (EFS). Twenty-seven couples provided serum on the day of oocyte retrieval. Unconjugated BPA was measured by HPLC with Coularray detection. Odds ratios (OR) were generated using ordinal logistic regression including female and male BPA concentrations, age and race, and day of embryo transfer for ECN. Inverse associations are suggested for male BPA with ECN (OR=0.70, P=0.069), and EFS (OR=0.54, P=0.009), but not for women. Male BPA exposure may affect embryo quality during IVF. |
| File Format | HTM / HTML |
| ISSN | 13826689 |
| e-ISSN | 18727077 |
| DOI | 10.1016/j.etap.2011.06.003 |
| Journal | Environmental Toxicology and Pharmacology |
| Issue Number | 2 |
| Volume Number | 32 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-09-01 |
| Publisher Place | Netherlands |
| Access Restriction | Open |
| Subject Keyword | Discipline Environmental Health Discipline Pharmacology Embryo, Mammalian Cytology Drug Effects Estrogens, Non-steroidal Blood Pharmacology Fertilization In Vitro Phenols Benzhydryl Compounds Physiology Odds Ratio |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology |
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