| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Bonnineau, C. Scaion, D. Lemaire, B. Belpaire, C. Thomé, J-P Thonon, M. Leermaker, M. Gao, Y. Debier, C. Silvestre, F. Kestemont, P. Rees, J-F |
| Description |
Country affiliation: Belgium Author Affiliation: Bonnineau C ( Université catholique de Louvain, Institut des Sciences de la Vie, Croix du Sud, 2/L7.05.08, B-1348 Louvain-la-Neuve, Belgium.); Scaion D ( Université catholique de Louvain, Institut des Sciences de la Vie, Croix du Sud, 2/L7.05.08, B-1348 Louvain-la-Neuve, Belgium.); Lemaire B ( Université catholique de Louvain, Institut des Sciences de la Vie, Croix du Sud, 2/L7.05.08, B-1348 Louvain-la-Neuve, Belgium.); Belpaire C ( Research Institute for Nature and Forest (INBO), Duboislaan 14, 1560 Hoeilaart, Belgium.); Thomé JP ( Laboratoire d'Ecologie animale et d'Ecotoxicologie, Institut de Zoologie, Université de Liège, Quai Van Beneden 22, 4020 Liège, Belgium.); Thonon M ( Laboratoire d'Ecologie animale et d'Ecotoxicologie, Institut de Zoologie, Université de Liège, Quai Van Beneden 22, 4020 Liège, Belgium.); Leermaker M ( Analytical and Environmental Chemistry, Department of Chemistry, Faculty of Science, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Elsene, Belgium.); Gao Y ( Analytical and Environmental Chemistry, Department of Chemistry, Faculty of Science, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Elsene, Belgium.); Debier C ( Université catholique de Louvain, Institut des Sciences de la Vie, Croix du Sud, 2/L7.05.08, B-1348 Louvain-la-Neuve, Belgium.); Silvestre F ( Unité de Recherche en Biologie Environnementale et Evolutive (URBE), Université de Namur, Rue de Bruxelles 61, B-5000, Namur, Belgium.); Kestemont P ( Unité de Recherche en Biologie Environnementale et Evolutive (URBE), Université de Namur, Rue de Bruxelles 61, B-5000, Namur, Belgium.); Rees JF ( Université catholique de Louvain, Institut des Sciences de la Vie, Croix du Sud, 2/L7.05.08, B-1348 Louvain-la-Neuve, Belgium. Electronic address: jf.rees@uclouvain.be.) |
| Abstract |
Xenobiotics such as organochlorine compounds (OCs) and metals have been suggested to play a significant role in the collapse of European eel stocks in the last decades. Several of these pollutants could affect functioning of the nervous system. Still, no information is so far available on levels of potentially neurotoxic pollutants in eel brain. In present study, carried out on female eels caught in Belgian rivers and canals, we analyzed brain levels of potentially-neurotoxic trace elements (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, MeHg, Mn, Ni, Pb, Sn, Sb, Zn) and OCs (Polychlorinated biphenyls, PCBs; Hexachlorocyclohexanes, HCHs; Dichlorodiphenyltrichloroethane and its metabolites, DDTs). Data were compared to levels in liver and muscle tissues. Eel brain contained very high amounts of OCs, superior to those found in the two other tissues. Interestingly, the relative abundance of PCB congeners markedly differed between tissues. In brain, a predominance of low chlorinated PCBs was noted, whereas highly chlorinated congeners prevailed in muscle and liver. HCHs were particularly abundant in brain, which contains the highest amounts of ß-HCH and Ï-HCH. p,p'-DDTs concentration was similar between brain and muscle (i.e., about twice that of liver). A higher proportion of p,p'-DDT was noticed in brain. Except for Cr and inorganic Hg, all potentially neurotoxic metals accumulated in brain to levels equal to or lower than hepatic levels. Altogether, results indicate that eel brain is an important target for organic and, to a lesser extent, for inorganic neurotoxic pollutants. |
| File Format |
HTM / HTML |
| ISSN |
13826689 |
| Journal |
Environmental Toxicology and Pharmacology |
| Volume Number |
45 |
| e-ISSN |
18727077 |
| Language |
English |
| Publisher |
Elsevier |
| Publisher Date |
2016-07-01 |
| Publisher Place |
Netherlands |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Environmental Health Discipline Pharmacology |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology |
