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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Li, Lingling Gao, Wei Yang, Xiao Wu, Dandan Bi, Hui Zhang, Sini Huang, Mao Yao, Xin |
| Description | Country affiliation: China Author Affiliation: Li L ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Gao W ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Yang X ( Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Wu D ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Bi H ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Zhang S ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Huang M ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.); Yao X ( Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: xyao1998@126.com.) |
| Abstract | BACKGROUND: Asthma is the most common chronic disease in children and a major public health problem in adults. A relation between asthma and toxocariasis has been hypothesized. OBJECTIVE: To evaluate the strength of association between asthma and Toxocara species seropositivity by conducting a systematic review and a meta-analysis of available data. METHODS: PubMed, EMBASE, Web of Science, and the reference lists of all relevant articles and books were screened until October 2013. Two authors independently assessed eligibility and study quality and extracted data. A common odds ratio was estimated using a random-effects meta-analysis model of aggregated published data. RESULTS: Ten studies met the inclusion criteria, for a total of 1,530 participants (723 cases and 807 controls). This meta-analysis found a significantly higher prevalence of Toxocara canis infection in patients with asthma than in controls (odds ratio 3.36, 95% confidence interval 1.76-6.42, P < .001). Similar results were found when meta-analysis was restricted to the studies considering only children or adults. CONCLUSION: The results support the existence of a positive association between asthma and Toxocara species seropositivity. |
| File Format | HTM / HTML |
| ISSN | 10811206 |
| Issue Number | 2 |
| Volume Number | 113 |
| e-ISSN | 15344436 |
| Journal | Annals of Allergy, Asthma & Immunology |
| Language | English |
| Publisher | Elsevier (on behalf of the American College of Allergy, Asthma and Immunology) |
| Publisher Date | 2014-08-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Immunology Asthma Epidemiology Toxocara Canis Immunology Toxocariasis Adolescent Adult Aged Animals Child Child, Preschool Female Humans Infant Male Middle Aged Prevalence Seroepidemiologic Studies Young Adult Journal Article Meta-analysis Research Support, Non-u.s. Gov't Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine Immunology and Allergy Immunology |
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