NDLI: Silent coronary artery disease in Japanese patients undergoing carotid artery stenting.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Enomoto, Yukiko Yoshimura, Shinichi Yamada, Kiyofumi Kawasaki, Masanori Nishigaki, Kazuhiko Minatoguchi, Shinya Iwama, Toru
Spatial Coverage	Japan
Description	Country affiliation: Japan Author Affiliation: Enomoto Y ( Department of Neurosurgery, Graduate School of Medicine, Gifu University, Gifu, Japan.)
Abstract	BACKGROUND: The aim of this retrospective study was to determine the prevalence of silent coronary artery disease (CAD) and the risk factors associated with concomitant CAD in Japanese patients undergoing carotid artery stenting (CAS). METHODS: The records of 112 consecutive patients (99 men and 13 women; mean age 70 ± 8 years) who underwent elective CAS at our institution for extracranial carotid artery stenosis between January 2006 and January 2011 were reviewed retrospectively. During this period, preoperative CAD screening by coronary angiography was performed in all patients. Patients were diagnosed with CAD when ≥ 1 coronary arteries had stenosis ≥ 75% and were classified into 2 groups: (1) a group with CAD that was based on preoperative coronary angiography or a history of percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG), and (2) a group without CAD that had no angiographically documented stenosis ≥ 75%. RESULTS: Sixteen (14.3%) patients had CAD that had already been treated by PCI and/or CABG. Silent CAD was detected in 39 (34.8%) of 112 patients. Taken together, 55 (49.1%) patients had clinically significant CAD. The patients with CAD were more likely to have diabetes mellitus (DM; P = .001), dyslipidemia (P = .013), and bilateral carotid disease (P = .033). Multivariate analysis revealed that DM (odds ratio 3.07; 95% confidence interval 1.25-7.53) and bilateral carotid stenosis (odds ratio 2.72; 95% confidence interval 1.10-6.75) were independent variables associated with concomitant CAD. CONCLUSIONS: Perioperative CAD screening revealed that silent CAD was frequently diagnosed in Japanese patients scheduled for CAS, particularly in those with DM and/or bilateral carotid stenosis.
File Format	HTM / HTML
ISSN	10523057
Issue Number	7
Volume Number	22
e-ISSN	15328511
Journal	Journal of Stroke and Cerebrovascular Diseases
Language	English
Publisher	Elsevier
Publisher Date	2013-10-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Carotid Arteries Complications Humans Japan Middle Aged Risk Factors Male Treatment Outcome Coronary Artery Disease Aged, 80 And Over Journal Article Asian Continental Ancestry Group Discipline Cardiology Surgery Coronary Artery Bypass Female Carotid Stenosis Aged Retrospective Studies Diagnosis Stents
Content Type	Text
Resource Type	Article
Subject	Rehabilitation Neurology (clinical) Surgery Cardiology and Cardiovascular Medicine

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