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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Deguchi, Kentaro Kono, Syoichiro Deguchi, Shoko Morimoto, Nobutoshi Kurata, Tomoko Ikeda, Yoshio Abe, Koji |
| Description | Country affiliation: Japan Author Affiliation: Deguchi K ( Department of Neurology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan.) |
| Abstract | Cognitive and affective impairments are important non-motor features of ischemic stroke (IS) related to white-matter hyperintensity, including periventricular hyperintensity (PVH). To confirm the usefulness of a novel computerized touch panel-type screening test, we investigated cognitive and affective functioning among 142 IS patients and 105 age-and gender-matched normal control subjects. Assessment using the mini-mental state examination, Hasegawa Dementia Scale-Revised, and frontal assessment battery revealed reduced cognitive function in IS patients, with the most severe reduction exhibited by cardiogenic embolism patients, followed by lacunar infarction patients, and atherothrombotic infarction patients. Our novel touch panel screening test revealed a similar pattern of results. In addition, PVH grading, classified using Fazekas' magnetic resonance imaging method, was also correlated with cognitive decline and touch panel screening test performance. In contrast, affective function, assessed with the 15-item Geriatric Depression Scale, vitality index, and apathy scale, was not significantly decreased in IS, and did not correlate with touch panel screening test results or PVH, although the number of microbleeds was correlated with apathy scale results. The present findings revealed that IS and PVH grading were significantly correlated with decline in general cognitive status (mini-mental state examination and Hasegawa Dementia Scale-Revised) and frontal lobe function (frontal assessment battery). Performance on all touch panel screening tests was correlated with IS and PVH grading, but was largely independent of depression or apathy. Touch panel screening tests were easily understood and performed by almost all patients with mild cognitive and motor dysfunction, due to visually clear images and simple methods not involving detailed manual-handling tasks such as writing. Touch panel screening tests may provide a useful tool for the early screening of cognitive function. |
| File Format | HTM / HTML |
| ISSN | 10523057 |
| Issue Number | 7 |
| Volume Number | 22 |
| e-ISSN | 15328511 |
| Journal | Journal of Stroke and Cerebrovascular Diseases |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-10-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Research Support, Non-u.s. Gov't Brain Ischemia Stroke Complications Psychology Humans Middle Aged Male Cognition Aged, 80 And Over Touch Journal Article Neuropsychological Tests Cognition Disorders Etiology Discipline Cardiology Female Physiology Aged Diagnosis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Rehabilitation Neurology (clinical) Surgery Cardiology and Cardiovascular Medicine |
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