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Production of lactic acid from sucrose: strain selection, fermentation, and kinetic modeling.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Lunelli, Betânia H. Andrade, Rafael R. Atala, Daniel I. P. Wolf Maciel, Maria Regina Maugeri Filho, Francisco Maciel Filho, Rubens
Description	Country affiliation: Brazil Author Affiliation: Lunelli BH ( Laboratory of Optimization, Design and Advanced Control, Department of Chemical Processes, School of Chemical Engineering, State University of Campinas, P.O. Box 6066, 13083-970 Campinas, São Paulo, Brazil. betania@feq.unicamp.br)
Abstract	Lactic acid is an important product arising from the anaerobic fermentation of sugars. It is used in the pharmaceutical, cosmetic, chemical, and food industries as well as for biodegradable polymer and green solvent production. In this work, several bacterial strains were isolated from industrial ethanol fermentation, and the most efficient strain for lactic acid production was selected. The fermentation was conducted in a batch system under anaerobic conditions for 50 h at a temperature of 34 degrees C, a pH value of 5.0, and an initial sucrose concentration of 12 g/L using diluted sugarcane molasses. Throughout the process, pulses of molasses were added in order to avoid the cell growth inhibition due to high sugar concentration as well as increased lactic acid concentrations. At the end of the fermentation, about 90% of sucrose was consumed to produce lactic acid and cells. A kinetic model has been developed to simulate the batch lactic acid fermentation results. The data obtained from the fermentation were used for determining the kinetic parameters of the model. The developed model for lactic acid production, growth cell, and sugar consumption simulates the experimental data well.
File Format	HTM / HTML
ISSN	02732289
Issue Number	1-8
Volume Number	161
e-ISSN	15590291
Journal	Applied Biochemistry and Biotechnology
Language	English
Publisher	Springer
Publisher Date	2010-05-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Biochemistry Discipline Biotechnology Fermentation Lactic Acid Biosynthesis Lactobacillaceae Metabolism Sucrose Bioreactors Microbiology Industrial Microbiology Methods Classification Models, Theoretical Molasses Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Medicine Molecular Biology Environmental Engineering Biochemistry Bioengineering Applied Microbiology and Biotechnology Biotechnology

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Production of Lactic Acid from Sucrose: Strain Selection, Fermentation, and Kinetic Modeling

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Production of lactic acid from the mixture of softwood pre-hydrolysate and paper mill sludge by simultaneous saccharification and fermentation.

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Production of lactic acid from sucrose: strain selection, fermentation, and kinetic modeling.

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Production of Lactic Acid from Sucrose: Strain Selection, Fermentation, and Kinetic Modeling

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