NDLI: Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Please wait, while we are loading the content...

Determination of lansoprazole enantiomers in dog plasma by column-switching liquid chromatography with tandem mass spectrometry and its application to a preclinical pharmacokinetic study.

Ionic liquid and aqueous two-phase extraction based on salting-out coupled with high-performance liquid chromatography for the determination of seven rare ginsenosides in Xue-Sai-Tong injection.

Ionic-liquid-impregnated resin for the microwave-assisted solid-liquid extraction of triazine herbicides in honey.

Retention behavior of resorcinarene-based cavitands on C8 and C18 stationary phases.

Organic monolith frits encased in polyether ether ketone tubing with improved durability for liquid chromatography.

Determination of diflubenzuron and chlorbenzuron in fruits by combining acetonitrile-based extraction with dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.

Multiresidue analysis of 36 pesticides in soil using a modified quick, easy, cheap, effective, rugged, and safe method by liquid chromatography with tandem quadruple linear ion trap mass spectrometry.

Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Purification of vandaterosides from Vanda teres (Orchidaceae) by stepwise gradient centrifugal partition chromatography.

Unified chromatography: Fundamentals, instrumentation and applications.

Optimizing the relationship between chromatographic efficiency and retention times in temperature-programmed gas chromatography.

Thermal desorption gas chromatography with mass spectrometry study of outgassing from polymethacrylimide foam (Rohacell®).

Optimization of microwave-assisted extraction for six inorganic and organic arsenic species in chicken tissues using response surface methodology

Rapidly differentiating grape seeds from different sources based on characteristic fingerprints using direct analysis in real time coupled with time-of-flight mass spectrometry combined with chemometrics.

Development of a method using high-performance liquid chromatographic fingerprint and multi-ingredients quantitative analysis for the quality control of Yangxinshi Pian.

Study of the forced degradation behavior of prasugrel hydrochloride by liquid chromatography with mass spectrometry and liquid chromatography with NMR detection and prediction of the toxicity of the characterized degradation products.

Elution-extrusion counter-current chromatography for the separation of two pairs of isomeric monoterpenes from Paeoniae Alba Radix.

Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization.

Impact of gas chromatography and mass spectrometry combined with gas chromatography and olfactometry for the sex differentiation of Baccharis articulata by the analysis of volatile compounds.

Preconcentration of indapamide from human urine using molecularly imprinted solid-phase extraction.

Simultaneous determination of three chloroacetic acids, three herbicides, and 12 anions in water by ion chromatography

Quality assessment of crude and processed ginger by high-performance liquid chromatography with diode array detection and mass spectrometry combined with chemometrics.

Year: 2015 Volume: 38 Issue: 16

Year: 2015 Volume: 38 Issue: 15

Year: 2015 Volume: 38 Issue: 14

Year: 2015 Volume: 38 Issue: 13

Year: 2015 Volume: 38 Issue: 12

Year: 2015 Volume: 38 Issue: 11

Year: 2015 Volume: 38 Issue: 10

Year: 2015 Volume: 38 Issue: 9

Year: 2015 Volume: 38 Issue: 8

Year: 2015 Volume: 38 Issue: 7

Year: 2015 Volume: 38 Issue: 6

Year: 2015 Volume: 38 Issue: 5

Year: 2015 Volume: 38 Issue: 4

Year: 2015 Volume: 38 Issue: 3

Year: 2015 Volume: 38 Issue: 2

Year: 2015 Volume: 38 Issue: 1

Year: 2014 Volume: 37

Year: 2013 Volume: 36

Year: 2012 Volume: 35

Year: 2011 Volume: 34

Year: 2010 Volume: 33

Year: 2009 Volume: 32

Year: 2008 Volume: 31

Year: 2007 Volume: 30

Year: 2005 Volume: 28

Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wittenberg, James B. Canas, Benjamin J. Zhou, Wanlong Wang, Perry G. Rua, Diego Krynitsky, Alexander J.
Description	Country affiliation: United States Author Affiliation: Wittenberg JB ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.); Canas BJ ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.); Zhou W ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.); Wang PG ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.); Rua D ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.); Krynitsky AJ ( U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD, USA.)
Abstract	Isothiazolinone biocides are broad-spectrum preservatives that are widely used in cosmetics, household, and industrial products. An increase in the number of cases of allergic contact dermatitis to isothiazolinone preservatives, namely, methylisothiazolinone and methylchloroisothiazolinone, have been recently noticed. The Food and Drug Administration relies on analytical methods to quantify levels of use of cosmetic ingredients and support enforcement action against products that are not in compliance with the law. In this study, an efficient ultra high performance liquid chromatography with tandem mass spectrometry method was developed and validated for the determination of methylisothiazolinone and methylchloroisothiazolinone in selected cosmetic products. The lower limit of quantitation was determined to be 0.1 µg/g for both preservatives. A survey of 24 cosmetic products was conducted and found concentrations of methylisothiazolinone and methylchloroisothiazolinone ranging from not quantified, or below the lower limit of quantitation, to 89.64 µg/g and not quantified to 10.31 µg/g, respectively.
File Format	HTM / HTML
ISSN	16159306
Issue Number	17
Volume Number	38
e-ISSN	16159314
Journal	Journal of Separation Science
Language	English
Publisher	Wiley-VCH
Publisher Date	2015-09-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Analytical Discipline Chemistry Chromatography, High Pressure Liquid Methods Tandem Mass Spectrometry Thiazoles Analysis Cosmetics Limit Of Detection Preservatives, Pharmaceutical Reference Standards Reproducibility Of Results Journal Article Research Support, U.s. Gov't, P.h.s.
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Filtration and Separation

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Rapid determination of quinolones in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Sensitive and rapid analytical method for the quantification of glucosamine in human plasma by ultra high performance liquid chromatography with tandem mass spectrometry.

Determination of isothiazolinone preservatives in cosmetics and household products by matrix solid-phase dispersion followed by high-performance liquid chromatography-tandem mass spectrometry.

A combined tryptic peptide and winged peptide internal standard approach for the determination of -lactalbumin in dairy products by ultra high performance liquid chromatography with tandem mass spectrometry.

Quality evaluation of Semen Cassiae (Cassia obtusifolia L.) by using ultra-high performance liquid chromatography coupled with mass spectrometry.

Simultaneous Determination of Five Components in Aster tataricus by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry.

Natural estrogens in dairy products: Determination of free and conjugated forms by ultra high performance liquid chromatography with tandem mass spectrometry.

Rapid extraction and determination of 25 bioactive constituents in Alpinia oxyphylla using microwave extraction with ultra high performance liquid chromatography with tandem mass spectrometry.

Determination of nicotine and its metabolites accumulated in fish tissue using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.

Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Similar Documents

Rapid determination of quinolones in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.

Sensitive and rapid analytical method for the quantification of glucosamine in human plasma by ultra high performance liquid chromatography with tandem mass spectrometry.

Determination of isothiazolinone preservatives in cosmetics and household products by matrix solid-phase dispersion followed by high-performance liquid chromatography-tandem mass spectrometry.

A combined tryptic peptide and winged peptide internal standard approach for the determination of -lactalbumin in dairy products by ultra high performance liquid chromatography with tandem mass spectrometry.

Quality evaluation of Semen Cassiae (Cassia obtusifolia L.) by using ultra-high performance liquid chromatography coupled with mass spectrometry.

Simultaneous Determination of Five Components in Aster tataricus by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry.

Natural estrogens in dairy products: Determination of free and conjugated forms by ultra high performance liquid chromatography with tandem mass spectrometry.

Rapid extraction and determination of 25 bioactive constituents in Alpinia oxyphylla using microwave extraction with ultra high performance liquid chromatography with tandem mass spectrometry.

Determination of nicotine and its metabolites accumulated in fish tissue using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.

Determination of methylisothiazolinone and methylchloroisothiazolinone in cosmetic products by ultra high performance liquid chromatography with tandem mass spectrometry.