NDLI: Case report: lady with bone pains for 5 years

Content Provider	Springer Nature : BioMed Central
Author	Rizwan, Azra Jamal, Abid Uzzaman, Maseeh Fatima, Saira
Abstract	Background Parathyroid cancer is a rare cause of primary hyperparathyroidism. It presents a diagnostic and therapeutic challenge that may not be recognized preoperatively, and is often not conclusively identified during the operation. We present the case of a lady with backache and hypercalcemia, but with inadequate work-up for her condition for several years. Case presentation A middle aged lady of Asian descent presented with backache. Initial work up revealed mild hypercalcemia, negative work up for multiple myeloma, negative sestamibi scan for parathyroid pathology. A phenomenally elevated parathormone (PTH) level—2105 pg/mL (16–87 pg/mL), and rising serum calcium, 15.1 mg/dL, (8.6–10.5 mg/dL), ordered years later prompted a repeat sestamibi scan and ultrasonography of neck. Based on these investigations, a diagnosis of primary hyperparathyroidism, with high suspicion of parathyroid cancer was made. The patient underwent surgical tumour resection, with subsequent histopathological confirmation of diagnosis. Conclusion In the setting of hypercalcemia, PTH level assessment is a must. This helps to differentiate between the parathyroid dependant and independent causes of high serum calcium, thereby encouraging a comprehensive pathway to the work up of the cause of hypercalcemia. The parathyroid cancer is a very rare cause of hypercalcemia, which needs to be considered in the differentials of primary hyperparathyroidism, particularly in the setting of high PTH levels.
Related Links	https://bmcresnotes.biomedcentral.com/counter/pdf/10.1186/s13104-018-3711-0.pdf
Ending Page	8
Page Count	8
Starting Page	1
File Format	HTM / HTML
ISSN	17560500
DOI	10.1186/s13104-018-3711-0
Journal	BMC Research Notes
Issue Number	1
Volume Number	11
Language	English
Publisher	BioMed Central
Publisher Date	2018-08-29
Access Restriction	Open
Subject Keyword	Biomedicine Medicine Public Health Life Sciences Parathormone (PTH) Sestamibi scan Hypercalcemia Primary hyperparathyroidism Case report Medicine/Public Health
Content Type	Text
Resource Type	Case study
Subject	Biochemistry, Genetics and Molecular Biology Medicine
Journal Impact Factor	1.6/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Anaesthetic Implications in Primary Hyperparathyroidism with Severe Hypercalcaemia; a Case Report

Sestamibi Positive Vs Negative Scan In Primary Hyperparathyroidism; A Clinical Dilemma

Primary Hyperparathyroidism Secondary to a Sestamibi-Negative Cystic Parathyroid Adenoma.

Giant parathyroid adenoma: a case report

Diagnostic challenge in parathyroid carcinoma with multiple pathological bone fracture: A case report

Parathyroid adenoma detected with 99mTc-tetrofosmin dual-phase scintigraphy: a case report

Bilateral giant parathyroid adenoma and hungry bone syndrome: a case report

Acute presentation of a giant intrathyroidal parathyroid adenoma: a case report

Primary hyperparathyroidism in a patient with primary aldosteronism

Case report: lady with bone pains for 5 years—parathyroid carcinoma

Similar Documents

Anaesthetic Implications in Primary Hyperparathyroidism with Severe Hypercalcaemia; a Case Report

Sestamibi Positive Vs Negative Scan In Primary Hyperparathyroidism; A Clinical Dilemma

Primary Hyperparathyroidism Secondary to a Sestamibi-Negative Cystic Parathyroid Adenoma.

Giant parathyroid adenoma: a case report

Diagnostic challenge in parathyroid carcinoma with multiple pathological bone fracture: A case report

Parathyroid adenoma detected with 99mTc-tetrofosmin dual-phase scintigraphy: a case report

Bilateral giant parathyroid adenoma and hungry bone syndrome: a case report

Acute presentation of a giant intrathyroidal parathyroid adenoma: a case report

Primary hyperparathyroidism in a patient with primary aldosteronism

Case report: lady with bone pains for 5 years—parathyroid carcinoma