NDLI: Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature

Content Provider	Springer Nature : BioMed Central
Author	Abdul-Ghafar, Jamshid Ahmad, Zubair Tariq, Muhammad Usman Kayani, Naila Uddin, Nasir
Abstract	Objective Lipoblastoma is a rare neoplasm that occurs mostly in infants and children. Although benign, it has a tendency for local recurrence. Results Clinical and pathological features of 23 cases of lipoblastoma described. Patients’ age ranged from 8 months to 18 years with mean and median age 4.1 and 2.5 years, respectively. Male:female ratio was 2.8:1. Most common sites were lower extremities (9 cases), followed by abdominal cavity and retroperitoneum (4 cases), and scrotum/groin (3 cases). Grossly, 22 tumors were well circumscribed and multi nodular. All cases showed lobules composed of adipocytes and lipoblasts with intervening fibrous septa and fine vascular network. Myxoid change, capsule formation and septation were seen in all cases. Zonation was seen in 2 cases. Follow-up was available in 14 out of 23 patients. Of these, 13 were alive and free of disease with no evidence of any recurrent lesion. One patient with a mediastinal infiltrating lipoblastoma experienced 4 recurrences. Lipoblastoma is a benign adipocytic neoplasm of infants and young children. Correlation of clinical and histological features helps in reaching a correct diagnosis. Owing to a high recurrence rate following incomplete resection, a complete resection is essential. Prognosis is excellent after complete resection.
Related Links	https://bmcresnotes.biomedcentral.com/counter/pdf/10.1186/s13104-018-3153-8.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
ISSN	17560500
DOI	10.1186/s13104-018-3153-8
Journal	BMC Research Notes
Issue Number	1
Volume Number	11
Language	English
Publisher	BioMed Central
Publisher Date	2018-01-17
Access Restriction	Open
Subject Keyword	Biomedicine Medicine Public Health Life Sciences Lipoblastoma Adipocyte Benign Recurrence Medicine/Public Health
Content Type	Text
Resource Type	Article
Subject	Biochemistry, Genetics and Molecular Biology Medicine
Journal Impact Factor	1.6/2023

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