NDLI: Pulmonary nocardiosis masquerading renascence of tuberculosis in an immunocompetent host: a case report from Nepal

Content Provider	Springer Nature : BioMed Central
Author	Khadka, Priyatam Basnet, Ramesh Bahadur Rijal, Basista Parsad Sherchand, Jeevan Bahadur
Abstract	Background Pulmonary nocardiosis is an opportunistic infection in an immunocompromised patient; however, often neglected in the immunocompetent patient from the diagnosis considerations. Case presentations We describe a case of pulmonary nocardiosis masquerading renascence of tuberculosis, in a 51-years-Nepali farmer. After a 6 month of presumed successful antitubercular therapy; the patient develops the clinical presentations and radiological features showing similarities with that of tuberculosis and malignancy. MTB complex was not detected with Xpert MTB/RIF assay and cytological examinations were negative for the malignant cells, however. The Ziehl–Neelsen staining of the broncho-alveolar-lavage revealed acid-fast, thin branching filamentous organisms suggestive Nocardia spp. Further, identifications and susceptibility pattern against recommended antibiotics were assessed as per the CLSI guidelines. The case was then, subsequently, diagnosed as pulmonary nocardiosis. Trimethoprim–sulfamethoxazole was prescribed for 12 months. The patient underwent progressive changes and no relapse was noted in a periodic follow-up. Conclusions This case underscores that pulmonary nocardiosis requires diagnostic considerations, regardless of a patient’s immunologic status and other mimicking infections.
Related Links	https://bmcresnotes.biomedcentral.com/counter/pdf/10.1186/s13104-018-3604-2.pdf
Ending Page	5
Page Count	5
Starting Page	1
File Format	HTM / HTML
ISSN	17560500
DOI	10.1186/s13104-018-3604-2
Journal	BMC Research Notes
Issue Number	1
Volume Number	11
Language	English
Publisher	BioMed Central
Publisher Date	2018-07-17
Access Restriction	Open
Subject Keyword	Biomedicine Medicine Public Health Life Sciences Immunocompetent host Pulmonary nocardiosis Tuberculosis Medicine/Public Health
Content Type	Text
Resource Type	Case study
Subject	Biochemistry, Genetics and Molecular Biology Medicine
Journal Impact Factor	1.6/2023

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