NDLI: Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study

Content Provider	Springer Nature : BioMed Central
Author	Feng, Lei Xie, Zexin Zhou, Xuetao Hou, Chunjuan Liang, Zheng Lu, Huiqing Liu, Lili Zhang, Dongsheng
Abstract	Objective This study aimed to investigate the role of D-dimer in the diagnosis of lower extremity deep venous thrombosis (DVT) in patients with rib fractures. Method Retrospective analysis was conducted on the clinical data of 499 patients with rib fractures who were admitted to the Third Hospital of Shijiazhuang between October 2020 and September 2021. These patients were divided into the DVT and the non-DVT groups. D-dimer levels were compared between the two groups at 24, 48, and 72 h after the injury. Receiver operating characteristic curves were utilized to evaluate the diagnostic efficacy of dynamically monitoring changes in D-dimer for DVT. Results The D-dimer levels in the DVT group were significantly higher than those in the non-DVT group at 24, 48, and 72 h after the injury. The area under the curve values for predicting DVT based on D-dimer level at 24, 48, and 72 h after injury in patients with rib fractures were 0.788, 0.605, and 0.568, respectively. Conclusion Detecting D-dimer levels 24 h after the injury can enhance diagnostic efficacy and sensitivity for DVT, thereby reducing the rate of missed diagnoses, which is of great clinical value.
Related Links	https://josr-online.biomedcentral.com/counter/pdf/10.1186/s13018-023-03997-x.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
DOI	10.1186/s13018-023-03997-x
Journal	Journal of Orthopaedic Surgery and Research
Issue Number	1
Volume Number	18
Language	English
Publisher	BioMed Central
Publisher Date	2023-07-20
Access Restriction	Open
Subject Keyword	Orthopedics Surgical Orthopedics D-dimer Fractured ribs Lower extremity deep venous thrombosis
Content Type	Text
Resource Type	Article
Subject	Surgery Orthopedics and Sports Medicine
Journal Impact Factor	2.8/2023
5-Year Journal Impact Factor	3/2023

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