NDLI: Comparison of cortical versus cancellous bone fixation in tendon-to-bone healing with a rat trans-calcaneal suture model for Achilles tendon sleeve avulsion

Content Provider	Springer Nature : BioMed Central
Author	Gao, Shang Hu, Chao Wang, Yunjiao Zhang, Jiqiang Tang, Kanglai
Abstract	Background Trans-calcaneal suture technique is an economical and effective method for repairing Achilles tendon sleeve avulsion. Whether cancellous bone fixation upon this technique could accelerate tendon-to-bone healing is unknown. The purpose of this study is to compare the effect of cortical versus cancellous bone fixation on tendon–bone healing with a novel rat trans-calcaneal suture model. Methods Trans-calcaneal suture treatment was carried out on the right hindlimb in male Sprague–Dawley rats (N = 80). They were randomly divided into the cortical group (Achilles fixed to the calcaneal cortical bone, n = 40) and the cancellous group (Achilles fixed to the calcaneal cancellous bone, n = 40). Gait analysis and immunohistochemistry were performed 1, 4, 7, and 14 days after the operation. Gross observation, biomechanical analysis, micro-CT, and histological analysis were performed 4 and 8 weeks after surgery. Independent-samples t tests were used for comparison between groups. Results At 1, 4, and 7 days, the swing time of the affected limb in the cancellous group decreased, while the duty cycle, the maximum contact area, the print area, and the mean intensity increased significantly. The cross-sectional area of the tendon–bone junction in the cancellous group was smaller, and the failure load and stiffness were higher 4 weeks after the operation. The cancellous group showed more proportion of new bone and a relatively well-organized and dense connective tissue interface with better fibrocartilage-like tissue at 4 weeks after the operation. The ratio of ED2 + macrophages in the cancellous group was significantly higher than in the cortical group on 1, 4, 7, and 14 days. There were no significant differences in gait at 2 weeks, in appearance, biomechanics, new bone formation, and histology at 8 weeks after surgery between the two groups. Conclusion In the new rat trans-calcaneal suture model, cancellous fixation can accelerate tendon-to-bone healing in the early stage, which perhaps is related to the abundant bone marrow tissue in the cancellous bone that modulates the inflammatory processes.
Related Links	https://josr-online.biomedcentral.com/counter/pdf/10.1186/s13018-022-03469-8.pdf
Ending Page	12
Page Count	12
Starting Page	1
File Format	HTM / HTML
DOI	10.1186/s13018-022-03469-8
Journal	Journal of Orthopaedic Surgery and Research
Issue Number	1
Volume Number	18
Language	English
Publisher	BioMed Central
Publisher Date	2023-01-05
Access Restriction	Open
Subject Keyword	Orthopedics Surgical Orthopedics Achilles tendon sleeve avulsion Tendon-to-bone healing Trans-calcaneal suture technique Rat model Cancellous bone Macrophage
Content Type	Text
Resource Type	Article
Subject	Surgery Orthopedics and Sports Medicine
Journal Impact Factor	2.8/2023
5-Year Journal Impact Factor	3/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Repair of Achilles sleeve avulsion: a new transosseous suture technique

Bone Anchor Suture Tape Fixation Technique for the Treatment of Calcaneal Avulsion Fractures

Repair of the achilles tendon sleeve avulsion: a transcalcaneal suture technique.

Ilizarov external fixation technique for repair of a calcaneal avulsion fracture and Achilles tendon rupture.

A novel and efficient murine model for investigating tendon-to-bone healing

Comparison of Bone Tunnel and Cortical Surface Tendon-to-Bone Healing in a Rabbit Model of Biceps Tenodesis

Achilles tenodesis for calcaneal insufficiency avulsion fractures associated with diabetes mellitus

Less Invasive Fixation of Acute Avulsions of the Achilles Tendon

Avulsion fracture of the calcaneal tuberosity: classification and its characteristics.

Comparison of cortical versus cancellous bone fixation in tendon-to-bone healing with a rat trans-calcaneal suture model for Achilles tendon sleeve avulsion

Similar Documents

Repair of Achilles sleeve avulsion: a new transosseous suture technique

Bone Anchor Suture Tape Fixation Technique for the Treatment of Calcaneal Avulsion Fractures

Repair of the achilles tendon sleeve avulsion: a transcalcaneal suture technique.

Ilizarov external fixation technique for repair of a calcaneal avulsion fracture and Achilles tendon rupture.

A novel and efficient murine model for investigating tendon-to-bone healing

Comparison of Bone Tunnel and Cortical Surface Tendon-to-Bone Healing in a Rabbit Model of Biceps Tenodesis

Achilles tenodesis for calcaneal insufficiency avulsion fractures associated with diabetes mellitus

Less Invasive Fixation of Acute Avulsions of the Achilles Tendon

Avulsion fracture of the calcaneal tuberosity: classification and its characteristics.

Comparison of cortical versus cancellous bone fixation in tendon-to-bone healing with a rat trans-calcaneal suture model for Achilles tendon sleeve avulsion