NDLI: A neuromechanical model characterizing the motor planning and posture control in the voluntary lean in Parkinson’s disease

Content Provider	Springer Nature : BioMed Central
Author	Jasimi Zindashti, Niromand Rahmati, Zahra Mohebbi, Abolfazl Behzadipour, Saeed
Abstract	Parkinson’s disease targets patients’ cognitive and motor abilities, including postural control. Many studies have been carried out to introduce mathematical models for a better understanding of postural control in such patients and the relation between the model parameters and the clinical assessments. So far, these studies have addressed this connection merely in static tests, such as quiet stance. The aim of this study is to develop a model for voluntary lean, and as such, identify the model parameters for both PD patients and healthy subjects from experimental data. The proposed model comprises planning and control sections. The model parameters for the planning section were extracted from the time response characteristics. Parameters for the control section were identified based on the spatial characteristics of the center-of-pressure (COP) response using an optimization process. 24 PD patients along with 24 matched healthy subjects participated in the study. The results showed a significant difference between the two groups in terms of temporal parameters for the planning section. This difference emphasizes bradykinesia as an essential symptom of PD. Also, differences were found for the postural control section. In all directions, the proportional gain of the feedback controller was significantly larger in PD patients; however, the gain of the feedforward controller was significantly smaller in PD patients. Furthermore, the control gains were strongly correlated with the clinical scales (Functional Reach Test and Unified Parkinson's Disease Rating Scale) in certain directions. In conclusion, the new model helps to better understand and quantify some PD symptoms in voluntary lean tasks.
Related Links	https://jneuroengrehab.biomedcentral.com/counter/pdf/10.1186/s12984-024-01321-0.pdf
Ending Page	12
Page Count	12
Starting Page	1
File Format	HTM / HTML
ISSN	17430003
DOI	10.1186/s12984-024-01321-0
Journal	Journal of NeuroEngineering and Rehabilitation
Issue Number	1
Volume Number	21
Language	English
Publisher	BioMed Central
Publisher Date	2024-02-15
Access Restriction	Open
Subject Keyword	Neurosciences Neurology Rehabilitation Medicine Biomedical Engineering and Bioengineering Parkinson’s disease Limit of stability Motor planning Postural control Computational modelling
Content Type	Text
Resource Type	Article
Subject	Health Informatics Rehabilitation
Journal Impact Factor	5.2/2023
5-Year Journal Impact Factor	5.6/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Disentangling stability and flexibility degrees in Parkinson’s disease using a computational postural control model

Effects of a balance-based exergaming intervention using the Kinect sensor on posture stability in individuals with Parkinson’s disease: a single-blinded randomized controlled trial

The quality of turning in Parkinson’s disease: a compensatory strategy to prevent postural instability?

Validity and sensitivity of instrumented postural and gait assessment using low-cost devices in Parkinson’s disease

ISway: a sensitive, valid and reliable measure of postural control

Effects of transcranial direct current stimulation (tDCS) on posture, movement planning, and execution during standing voluntary reach following stroke

The influence of posture duration on hand tremor during tasks with attention-distraction in persons with Parkinson’s disease

Audio-Biofeedback training for posture and balance in Patients with Parkinson's disease

SPARC: a new approach to quantifying gait smoothness in patients with Parkinson’s disease

A neuromechanical model characterizing the motor planning and posture control in the voluntary lean in Parkinson’s disease

Similar Documents

Disentangling stability and flexibility degrees in Parkinson’s disease using a computational postural control model

Effects of a balance-based exergaming intervention using the Kinect sensor on posture stability in individuals with Parkinson’s disease: a single-blinded randomized controlled trial

The quality of turning in Parkinson’s disease: a compensatory strategy to prevent postural instability?

Validity and sensitivity of instrumented postural and gait assessment using low-cost devices in Parkinson’s disease

ISway: a sensitive, valid and reliable measure of postural control

Effects of transcranial direct current stimulation (tDCS) on posture, movement planning, and execution during standing voluntary reach following stroke

The influence of posture duration on hand tremor during tasks with attention-distraction in persons with Parkinson’s disease

Audio-Biofeedback training for posture and balance in Patients with Parkinson's disease

SPARC: a new approach to quantifying gait smoothness in patients with Parkinson’s disease

A neuromechanical model characterizing the motor planning and posture control in the voluntary lean in Parkinson’s disease