NDLI: Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice

Content Provider	Springer Nature Link
Author	Milovavich, Ivan D. Ćirković, Saša De Luka, Silvio R. Djordjevich, Drago M. Ilić, Andjelija Ž. Popović, Tamara Arsić, Aleksandra Obradović, Danilo D. Oprić, Dejan Ristić Djurović, Jasna L. Trbovich, Alexander M.
Copyright Year	2015
Abstract	It has been shown that static magnetic field (SMF) of moderate intensity produces considerable impact on biological systems. SMF can be homogeneous or inhomogeneous. In many studies, inhomogeneous SMF was employed. Aware that inhomogeneous SMF could result in experimental variability, we investigated the influence of a vertical homogeneous SMF of different orientation. Male Swiss-Webster 9- to 10-week-old mice were subacutely exposed to upward- and downward-oriented SMF of 128 mT generated by a cyclotron for 1 h/day during a 5-day period. We found that SMF affected various organs and that these effects were, to some degree, dependent on SMF orientation. Both upward- and downward-oriented SMF caused a reduction in the amount of total white blood cells (WBC) and lymphocytes in serum, a decrease of granulocytes in the spleen, kidney inflammation, and an increase in the amount of high-density lipoprotein (HDL). In addition, upward-oriented SMF caused brain edema and increased spleen cellularity. In contrast, downward-oriented SMF induced liver inflammation and a decrease in the amount of serum granulocytes. These effects might represent a specific redistribution of pro-inflammatory cells in blood and among various organs. It appears that homogeneous SMF of 128 mT affected specific organs in the body, rather than simultaneously and equally influencing the entire body system.
Starting Page	1584
Ending Page	1597
Page Count	14
File Format	PDF
ISSN	09441344
Journal	Environmental Science and Pollution Research
Volume Number	23
Issue Number	2
e-ISSN	16147499
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-09-17
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Homogeneous static magnetic field of different orientation Liver Brain Kidney Spleen Serum Environment Environmental Chemistry Ecotoxicology Environmental Health Atmospheric Protection/Air Quality Control/Air Pollution Waste Water Technology Water Pollution Control Water Management Aquatic Pollution
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis Pollution Medicine

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