NDLI: Changes in Phospholipid Composition of Synaptic Membranes in Frontal Lobes of Cerebral Hemispheres in Cats at Various Stages of Hemorrhagic Shock

Content Provider	Springer Nature Link
Author	Leskova, G. F.
Copyright Year	2008
Abstract	Phospholipid composition of synaptic membranes in the frontal lobes of cerebral hemispheres was studied in cats with hemorrhagic shock. The compensatory and adaptive mechanisms of regulation of neurotransmission in this region of the brain at the initial stage of hemorrhagic shock are associated with increased degradation of phosphatidylinositol. Accumulation of this phospholipid in synaptic membranes during severe hemorrhagic shock reflects instability of the key neuroregulatory pathway, which is mediated by phosphatidylinositol metabolites. Dysregulation of transmembrane signaling in hemorrhagic shock is related to depletion of phosphatidylcholine and phosphatidylserine in synaptic membranes and accumulation of phosphatidylethanolamine.
Starting Page	401
Ending Page	404
Page Count	4
File Format	PDF
ISSN	00074888
Journal	Bulletin of Experimental Biology and Medicine
Volume Number	146
Issue Number	4
e-ISSN	15738221
Language	English
Publisher	Springer US
Publisher Date	2009-02-11
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	phospholipids synaptic membranes hemorrhagic shock Laboratory Medicine Pathology Cell Biology Internal Medicine Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Changes in Phospholipid Composition of Synaptic Membranes in Frontal Lobes of Cerebral Hemispheres in Cats at Various Stages of Hemorrhagic Shock