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| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Cao, Wen-Jun Ou, Shi-Yi Lin, Wei-Feng Tang, Chuan-He |
| Copyright Year | 2016 |
| Abstract | The development of food-grade (nano)particles as a delivery system for poorly water soluble bioactives has recently attracted increasing attention. This work is an attempt to fabricate food protein-based nanoparticles as delivery systems for improving the water dispersion and bioaccessibility of phytosterols (PS) by an emulsification–evaporation method. The fabricated PS nanoparticles were characterized in terms of particle size, encapsulation efficiency (EE%) and loading amount (LA), and ξ-potential. Among all the test proteins, including soy protein isolate (SPI), whey protein concentrate (WPC) and sodium caseinate (SC), SC was confirmed to be the most suitable protein for the PS nano-formulation. Besides the type of protein, the particle size, EE% and LA of PS in the nanoparticles varied with the applied protein concentration in the aqueous phase and organic volume fraction. The freeze-dried PS nanoparticles with SC exhibited good water re-dispersion behavior and low crystallinity of PS. The LA of PS in the nanoparticles decreased upon storage, especially at high temperatures (e.g., >25 °C). The PS in the fabricated nanoparticles exhibited much better bioaccessibility than free PS. The findings would be of relevance for the fabrication of food-grade colloidal phytosterols, with great potential to be applied in functional food formulations. |
| Starting Page | 3973 |
| Ending Page | 3980 |
| Page Count | 8 |
| File Format | HTM / HTML PDF |
| ISSN | 20426496 |
| Volume Number | 7 |
| Issue Number | 9 |
| Journal | Food & Function |
| DOI | 10.1039/c6fo00861e |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Open |
| Subject Keyword | WPC SC LA of PS LA Dispersion relation Los Angeles Soy protein Whey protein Casein Protein Freeze-drying Functional food |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Food Science |
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