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| Content Provider | PubMed Central |
|---|---|
| Author | Khoo, Hock Eng Azlan, Azrina Nurulhuda, M. Halid Ismail, Amin Abas, Faridah Hamid, Muhajir Suri, Roowi |
| Copyright Year | 2013 |
| Abstract | This study aimed to determine anthocyanins and their antioxidative and cardioprotective properties in defatted dabai parts. Anthocyanins in crude extracts and extract fractions of defatted dabai peel and pericarp were quantified using UHPLC, while their antioxidant capacity and oxidative stress inhibition ability were evaluated by using DPPH and CUPRAC assays as well as linoleic acid oxidation system, hemoglobin oxidation, and PARP-1 inhibition ELISA. Cardioprotective effect of the defatted dabai peel extract was evaluated using hypercholesterolemic-induced New Zealand white rabbits. Six anthocyanins were detected in the defatted dabai peel, with the highest antioxidant capacities and oxidative stress inhibition effect compared to the other part. The defatted dabai peel extract has also inhibited lipid peroxidation (plasma MDA) and elevated cellular antioxidant enzymes (SOD and GPx) in the tested animal model. Major anthocyanin (cyanidin-3-glucoside) and other anthocyanins (pelargonidin-3-glucoside, malvidin-3-glucoside, cyanidin-3-galactoside, cyanidin-3-arabinoside, and peonidin-3-glucoside) detected in the defatted dabai peel are potential future nutraceuticals with promising medicinal properties. |
| Related Links | http://dx.doi.org/10.1155/2013/434057 |
| Starting Page | 434057 |
| File Format | |
| ISSN | 1741427X |
| e-ISSN | 17414288 |
| Journal | Evidence-based Complementary and Alternative Medicine : eCAM |
| Volume Number | 2013 |
| Language | English |
| Publisher | Hindawi Publishing Corporation |
| Publisher Date | 2013-01-01 |
| Access Restriction | Open |
| Rights Holder | Hindawi Publishing Corporation |
| Subject Keyword | Complementary and alternative medicine Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Complementary and Alternative Medicine |
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