NDLI: Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing

Content Provider	PubMed Central
Author	Barud, Hernane Da Silva Júnior, Adalberto Miguel De Araújo Saska, Sybele Boldrin, Mestieri Letícia Campos, Juliana Alvares Duarte Bonini Freitas, Rubens Moreno De Ferreira, Nathália Ursoli Nascimento, Andresa Piacezzi Miguel, Felipe Galeti Vaz, Mirela Mara De Oliveira Lima Leite Aparecida, Barizon Edna Marquele-oliveira, Franciane Gaspar, Ana Maria Minarelli Ribeiro, Sidney José Lima Berretta, Andresa Aparecida
Copyright Year	2013
Abstract	Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, and mainly its antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this and knowing the distinctive performance of bacterial (BC) membranes on wound healing, in this work it is proposed to demonstrate the potent antimicrobial activity and wound healing properties of a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able to adsorb propolis not only on the surface, but also in its interstices demonstrated by scanning electron microscopy, X-ray diffraction, Fourier transform infrared (FT-IR) spectroscopy, and thermogravidimetric assays. Additionally, the polyphenolic compounds determination and the prominent antibacterial activity in the membrane are demonstrated to be dose dependent, supporting the possibility of obtaining propolis/BC membranes at the desired concentrations, taking into consideration its application and its skin residence time. Finally, it could be suggested that propolis/BC membrane may favor tissue repair in less time and more effectively in contaminated wounds.
Related Links	http://dx.doi.org/10.1155/2013/703024
Starting Page	703024
File Format	PDF
ISSN	1741427X
e-ISSN	17414288
Journal	Evidence-based Complementary and Alternative Medicine : eCAM
Volume Number	2013
Language	English
Publisher	Hindawi Publishing Corporation
Publisher Date	2013-01-01
Access Restriction	Open
Rights Holder	Hindawi Publishing Corporation
Subject Keyword	Complementary and alternative medicine Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Complementary and Alternative Medicine

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