NDLI: Biological Activities and Chemical Characterization of Cordia verbenacea DC. as Tool to Validate the Ethnobiological Usage

Content Provider	PubMed Central
Author	Matias, Edinardo Fagner Ferreira Alves, Erivânia Ferreira Santos, Beatriz Sousa Souza, Celestina Elba Sobral De Ferreira, João Victor De Alencar Santos, De Lavor Anne Karyzia Lima Figueredo, Fernando Gomes Lima, Luciene Ferreira De Santos, Francisco Antônio Vieira Dos Peixoto, Flórido Sampaio Neves Viana, Colares Aracélio Augusti, Boligon Aline Saraiva, Rogério De Aquino Athayde, Margareth Linde Rocha, João Batista Teixeira Da Menezes, Irwin Rose Alencar Coutinho, Henrique Douglas Melo Costa, José Galberto Martins Da
Copyright Year	2013
Abstract	Knowledge of medicinal plants is often the only therapeutic resource of many communities and ethnic groups. “Erva-baleeira”, Cordia verbenacea DC., is one of the species of plants currently exploited for the purpose of producing a phytotherapeutic product extracted from its leaves. In Brazil, its major distribution is in the region of the Atlantic Forest and similar vegetation. The crude extract is utilized in popular cultures in the form of hydroalcoholic, decoctions and infusions, mainly as antimicrobial, anti-inflammatory and analgesic agents. The aim of the present study was to establish a chemical and comparative profile of the experimental antibacterial activity and resistance modifying activity with ethnopharmacological reports. Phytochemical prospecting and HPLC analysis of the extract and fractions were in agreement with the literature with regard to the presence of secondary metabolites (tannins and flavonoids). The extract and fraction tested did not show clinically relevant antibacterial activity, but a synergistic effect was observed when combined with antibiotic, potentiating the antibacterial effect of aminoglycosides. We conclude that tests of antibacterial activity and modulating the resistance presented in this work results confirm the ethnobotanical and ethnopharmacological information, serving as a parameter in the search for new alternatives for the treatment of diseases.
Related Links	http://dx.doi.org/10.1155/2013/164215
Starting Page	164215
File Format	PDF
ISSN	17414288
e-ISSN	17414288
Journal	Evidence-based Complementary and Alternative Medicine : eCAM
Volume Number	2013
Language	English
Publisher	Hindawi Publishing Corporation
Publisher Date	2013-01-01
Access Restriction	Open
Rights Holder	Hindawi Publishing Corporation
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Complementary and Alternative Medicine

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