NDLI: Improvement of Qing Nao Tong Luo recipe on learning and memory impairment in senile dementia rats

Content Provider	IEEE Xplore Digital Library
Author	Jingbo Sun Rong Hua Zijun Hou Yinzhe Gui Yan Huang
Copyright Year	2011
Description	Author affiliation: Guangzhou University of Traditional Chinese Medicine, Guangzhou, China, 510006 (Zijun Hou; Yinzhe Gui) \|\| Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China, 510120 (Jingbo Sun; Rong Hua; Yan Huang)
Abstract	The purpose of this study was to observe the effects of Qing Nao Tong Luo Recipe (QNTL recipe) on learning and memory impairment in senile dementia rats and its effect on hippocampal synaptic plasticity. The Alzheimer's disease model was induced by D-galactose (D-gal) ip injection and Ibotenic acid microinjection into the basal forebrain area. Morris water maze task was used to evaluate the learning and memory function. Transmission electron microscope was used to observe the brain sections. Stereological analysis was used to analyze the synaptic density. The QNTL recipe has significant improvement on learning and memory dysfunction and hippocampal synaptic structural reconstruction of AD rats.
Starting Page	752
Ending Page	756
File Size	734234
Page Count	5
File Format	PDF
ISBN	9781457716126
e-ISBN	9781457716133
DOI	10.1109/BIBMW.2011.6112465
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-11-12
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Training Analytical models learning and memory impairment Aging Rats synaptic plasticity Alzheimer's disease Hippocampus Dementia disease model Traditional Chinese Medicine
Content Type	Text
Resource Type	Article

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