NDLI: Assessment of regional myocardial strain using cardiac elastography: distinguishing infarcted from non-infarcted myocardium

Content Provider	IEEE Xplore Digital Library
Author	Konofagou, E.E. Harrigan, T. Solomon, S.
Copyright Year	2001
Description	Author affiliation: Dept. of Radiol., Brigham & Women's Hosp., Boston, MA, USA (Konofagou, E.E.)
Abstract	Estimation of the regional mechanical properties of the cardiac muscle has been shown to play a crucial role in the detection of cardiovascular disease. Current echocardiography-based cardiac motion estimation techniques, such as Doppler Myocardial Imaging (DMI), are limited due to angle dependence. By contrast, elastography, a method designed and used for the detection of tumors, measures displacement and strain by comparing echoes before and after (not during) a deformation and thus is not angle-dependent. Therefore, the feasibility of cardiac elastography to provide reliable and reproducible displacement and strain estimates from multiple sonographic views was recently demonstrated utilizing RF data from a normal human heart in vivo. In this paper, we demonstrate this technique utilizing 2D B-scan data in a patient with a known myocardial infarction. Envelope-detected sonographic data was used to estimate regional wall motion and deformation. Displacement and strain estimates were obtained in both non-infarcted, normally contracting and infarcted regions. By obtaining cine-loop and M-Mode elastograms from both regions, the ischemic regions could be identified. In conclusion, elastography may be a clinically viable method for detection of abnormalities of regional wall motion throughout the cardiac cycle.
Sponsorship	Ultrasonics, Ferroelectr., & Frequency Control Soc
Starting Page	1589
Ending Page	1592
File Size	495598
Page Count	4
File Format	PDF
ISBN	0780371771
DOI	10.1109/ULTSYM.2001.992025
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-10-07
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Myocardium Capacitive sensors Motion estimation Strain measurement Mechanical factors Muscles Cardiovascular diseases Design methodology Neoplasms Displacement measurement
Content Type	Text
Resource Type	Article

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