NDLI: Young's modulus measurements of human liver and correlation with pathological findings

Content Provider	IEEE Xplore Digital Library
Author	Wen-Chun Yeh Yung-Ming Jeng Hey-Chi Hsu Po-Ling Kuo Meng-Lin Li Pei-Ming Yang Po Huang Lee Pai-Chi Li
Copyright Year	2001
Description	Author affiliation: Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan (Wen-Chun Yeh)
Abstract	Viral hepatitis causes fibrosis in liver and may change liver's mechanical properties. To evaluate the impact of fibrosis on elastic properties of human liver and to investigate potential benefits of ultrasonic elasticity imaging, nineteen fresh human liver samples and one hepatic tumor (focal nodular hyperplasia) sample obtained during operations were studied. Simple ID estimates based on the cyclic compression-relaxation method were preformed. Young's modulus values were derived from the pre-determined strain (controlled by a step motor system) and the stress values (measured by an electronic balance). Each specimen subsequently received histological examination and a grade of liver fibrosis was scored from 0 to 5. Results show that the Young's modulus values were at the order of several hundreds to thousands Pascals. The Young's modulus generally increased with the fibrosis grade though some discrepancies existed at the middle grades of fibrosis (score 1-3). The correlation between the fibrosis score and the Young's modulus was significant (P<0.01) based on the statistical analysis using the Pearson correlation method.
Sponsorship	Ultrasonics, Ferroelectr., & Frequency Control Soc
Starting Page	1233
Ending Page	1236
File Size	247411
Page Count	4
File Format	PDF
ISBN	0780371771
DOI	10.1109/ULTSYM.2001.991942
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-10-07
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Anthropometry Humans Strain measurement Ultrasonic variables measurement Liver diseases Mechanical factors Elasticity Ultrasonic imaging Liver neoplasms Stress control
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in