NDLI: Development of fabrication and detection system for centrifugal force and thermal management biochip

Content Provider	IEEE Xplore Digital Library
Author	Ming-Yih Lee Chen-Ya Wang Huang-Chia Lin Hung-Wei Chiang Liang-Shiuan Su Tsung-Wei Chang
Copyright Year	2005
Description	Author affiliation: Graduate Inst. of Med. Mechatronics, Chang Gung Univ., Tao-Yuan, Taiwan (Ming-Yih Lee; Chen-Ya Wang; Huang-Chia Lin)
Abstract	The development of micro-electro-mechanical systems (MEMS) advances the success of microfabricated devices, and microfabricated devices offer many specific platforms that can integrate a laboratory on a chip and manage micro biochemical reaction analysis. Nevertheless, most microfabricated devices, especially in biochip design, depend on semi-conductor or LIGA process so that the configuration of devices is complex and money-consumed. Furthermore, miniaturization in nano-scale isn't always significant in bio-medical reactions. Thus, the aim of our research is to develop a fabrication and detection system of centrifugal-force and thermal management biochip, which improves the complex pumps and valves designed by semi-conductor application in lab-on-a-chip, and it saves time and money in the comparison of traditional lab technology. Our system uses the soft-ware-SolidWorks and computer numerical control (CNC) machine to design microfluidic patterns, the heat pressure machine with feedback control of temperature sensor to design the hermetically sealed biochip, and the centrifugal machine with server frequency conversion motor to lead sample mobility by centrifugal force instead of pumps and valves. The hardware of this system includes three parts: centrifugal machine, heat pressure machine, and microfluidic fabrication; the application of the biochip is to detect clinical and medicine bio-reactions. Our "fabrication and detection system for centrifugal-force and thermal management biochip" developed in this study is a on-table facility and can use in several areas of medical and clinical examinations, it can also combine with polymerase chain reaction (PCR) by adding temperature controlling procedure in the future.
Sponsorship	IEEE Ind. Electron. Soc. (IES) Chinese Inst. of Autom. Eng. (CIAE) Nat. Sci. Council, Taiwan, R.O.C. Minist. of Educ., Taiwan, R.O.C
Starting Page	903
Ending Page	908
File Size	879660
Page Count	6
File Format	PDF
ISBN	0780389980
DOI	10.1109/ICMECH.2005.1529382
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-07-10
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Thermal force Thermal management Fabrication Pumps Valves Computer numerical control Microfluidics Metalworking machines Microelectromechanical systems Micromechanical devices
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in