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Content Provider | IEEE Xplore Digital Library |
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Author | Mross, S. Furst, P. Pierrat, S. Zimmermann, T. Kraft, M. |
Copyright Year | 2014 |
Description | Author affiliation: Fraunhofer Inst. for Microelectron. Circuits & Syst., Duisburg, Germany (Mross, S.; Furst, P.; Pierrat, S.; Zimmermann, T.; Kraft, M.) |
Abstract | We report on an electrochemical measurement setup comprising a CMOS potentiostat and a glucose sensor with a two-layer membrane as the first steps towards the development of an integrated in-situ sensor system for bioreactors. The potentiostat has a chip size of 2.1 × 2.5 mm2 and a linear current range from -220 nA to 240 nA with a linearity of R2 = 0.9995. For wide range measurements of glucose concentrations in cell culture media, electrodes functionalized with the enzyme glucose oxidase were spin-coated with membranes made from polydimethylsiloxane (PDMS). With these membranes, glucose concentrations up to 400 mM were measured with a linear measurement range up to 100 mM. For interferent elimination, cellulose acetate membranes were employed. |
Starting Page | 1096 |
Ending Page | 1099 |
File Size | 942372 |
Page Count | 4 |
File Format | |
ISBN | 9781479901623 |
DOI | 10.1109/ICSENS.2014.6985196 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2014-11-02 |
Publisher Place | Spain |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Sugar Biomembranes Electrodes Biochemistry Current measurement Bioreactors Time factors CMOS potentiostat glucose sensor wide range measurement high glucose concentrations bioreactor monitoring membrane PDMS cellulose acetate |
Content Type | Text |
Resource Type | Article |
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