NDLI: An analytical scatter correction for singles-mode transmission data in PET

Content Provider	IEEE Xplore Digital Library
Author	Vandervoort, E. Sossi, V.
Copyright Year	2006
Description	Author affiliation: Dept. of Phys. & Astron., British Columbia Univ., Vancouver, BC (Vandervoort, E.; Sossi, V.)
Abstract	We present a scatter correction for singles-mode transmission data and its implementation as part of an iterative image reconstruction algorithm (OSTR). We compared our scatter calculation data with previously validated simulation data for three uniform water cylinders (radii of 25, 30 and 45 mm) using $^{68}Ge$ (a positron emitter) and $^{57}Co$ (122 keV photon emitter) transmission sources. Our scatter correction correctly predicts the contribution from single-scattered (one Compton interaction) photons to the sinogram data. Our correction also provides good agreement for the percent scatter fraction (SF) per sinogram for all phantom sizes and both transmission sources. We applied our scatter correction to experimental data from the microPET Focus 120 small animal scanner for three different sized uniform water cylinders and for a non-uniform phantom consisting of water, Teflon and air. The reconstructed linear attenuation coefficients (mu-values) agreed with expected values to within 4% for both the $^{68}Ge$ and $^{57}Co$ transmission sources and all phantoms. Using a 2.2 GHz processor our scatter correction requires between 7 to 20 minutes of CPU time depending on the phantom size and source used. This extra calculation time does not seem unreasonable considering that, without scatter corrections, errors in the reconstructed mu-values were between 28 to 40% depending on the phantom size and transmission source used. Simple rescaling or segmentation of uncorrected mu-map images does not provide an adequate alternative to scatter correction, since these errors depend on the radial position within an image slice and can be on the order of the difference between the mu-values for water and bone.
Starting Page	3310
Ending Page	3314
File Size	253038
Page Count	5
File Format	PDF
ISBN	1424405602
ISSN	10957863
DOI	10.1109/NSSMIC.2006.353714
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-10-29
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Electromagnetic scattering Particle scattering Imaging phantoms Image reconstruction Error correction Iterative algorithms Water resources Focusing Animals
Content Type	Text
Resource Type	Article

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