NDLI: Effect on lesion detectability of proximity to anatomical boundaries in emission tomography

Content Provider	IEEE Xplore Digital Library
Author	Kulkarni, S. Khurd, P. Hsiao, I. Gindi, G.
Copyright Year	2005
Description	Author affiliation: Dept. of Electr. & Comput. Eng., SUNY, Stony Brook, NY, USA (Kulkarni, S.)
Abstract	In emission tomography (ET) comprising PET and SPECT, anatomical information derived from intra-patient coregistered CT or MR scans can be incorporated into the ET reconstruction. The increasing availability of PET-CT and SPECT-CT has engendered renewed interest in anatomical priors. Our interest is in exploring the efficacy of such side information for lesion detectability. In simulation studies we used an idealized model of anatomical side information incorporated into a SPECT MAP (maximum a posteriori) reconstruction, and a channelized Hotelling observer (CHO) whose performance emulates that of humans in such detection tasks. We observed that detectability appears to vary little with or without anatomical side information unless the lesion is tightly constrained by anatomical boundaries. Our preliminary studies thus imply a limited utility for anatomical side information for this task.
Starting Page	2150
Ending Page	2154
File Size	291774
Page Count	5
File Format	PDF
ISBN	0780392213
ISSN	10957863
DOI	10.1109/NSSMIC.2005.1596760
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-10-23
Publisher Place	Puerto Rico
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Lesions Image reconstruction Computed tomography Smoothing methods Positron emission tomography Humans Brain Epilepsy Tumors Torso
Content Type	Text
Resource Type	Article

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