NDLI: Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT

Content Provider	IEEE Xplore Digital Library
Author	Taek-Soo Lee Segars, W.P. Tsui, B.M.W.
Copyright Year	2005
Description	Author affiliation: Dept. of Environ. Health Sci., Johns Hopkins Univ., Baltimore, MD, USA (Taek-Soo Lee)
Abstract	We investigate the optimal parameters of the 4D space-time Gibbs priors used in the 4D MAP-RBI-EM method for application to gated myocardial perfusion (GMP) SPECT. The Gibbs prior can be defined by a clique structure, the derivative of a generalized potential function (DGPF) with 3 parameters, and the overall weight of the prior. We used simulated data from a realistic 4D NCAT phantom modeling the uptake distribution of Tc-99m Sestamibi and the detected counts of a typical GMP SPECT study. The cardiac cycle was divided into 8, 16, 24 and 36 gates with the same total acquisition time. The normalized mean squared error (NMSE) and normalized standard deviation (NSD) were used to describe the spatial and temporal resolution, and image noise magnitude, respectively. The optimized values were determined as those that minimize both NMSE and NSD simultaneously. The phantom-matching motion error (PME) was calculated for the motion error between the motions of the left ventricular (LV) wall in the reconstructed images and the corresponding phantom slices. The results show the 4D MAP-RBI-EM with optimized parameters provides substantial improved reconstructed image quality as compared to the 3D OS-EM method with and without correction of other image degrading factors. We conclude that the 4D MAP-RBI-EM provides significantly higher GMP SPECT image quality with less motion error thus enabling more number of cardiac gates in GMP SPECT resulting in better visualization of LV wall motion.
Starting Page	2124
Ending Page	2128
File Size	438529
Page Count	5
File Format	PDF
ISBN	0780392213
ISSN	10957863
DOI	10.1109/NSSMIC.2005.1596754
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-10-23
Publisher Place	Puerto Rico
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Myocardium Image reconstruction Telephony Imaging phantoms Image quality Radiology Spatial resolution Image resolution Optimization methods Degradation
Content Type	Text
Resource Type	Article

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